T. Bruce Brown

Triazole oxytocin antagonists: Identification of an aryloxyazetidine replacement for a biaryl substituent

Alan D. Brown, T. Bruce Brown, Andrew Calabrese et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 73 citations · Full text

Pharmacological Study, Biaryl Substituent, Triazole Oxytocin Antagonists +8

Chiral relay in NHC-mediated asymmetric β-lactam synthesis I; substituent effects in NHCs derived from (1R,2R)-cyclohexane-1,2-diamine

Nicolas Duguet, Adele Donaldson, Stuart M. Leckie et al. · Tetrahedron Asymmetry · 2010 · 47 citations

Engineering, Chiral Relay, Substituent Effects +6

Discovery of a Selective Small-Molecule Melanocortin-4 Receptor Agonist with Efficacy in a Pilot Study of Sexual Dysfunction in Humans

Mark I. Lansdell, David Hepworth, Andrew Calabrese et al. · Journal of Medicinal Chemistry · 2010 · 38 citations · Full text

Sexual Health, Urology, Erectile Dysfunction +15

NHC-mediated enantioselective formal [4 + 2] cycloadditions of alkylarylketenes and β,γ-unsaturated α-ketocarboxylic esters and amides

Stuart M. Leckie, T. Bruce Brown, David C. Pryde et al. · Organic & Biomolecular Chemistry · 2013 · 33 citations

Dr Syn, Derivatives, Engineering +13

Chiral relay in NHC-mediated asymmetric β-lactam synthesis II; asymmetry from NHCs derived from acyclic 1,2-diamines

Nicolas Duguet, Adele Donaldson, Stuart M. Leckie et al. · Tetrahedron Asymmetry · 2010 · 33 citations

Engineering, Chiral Relay, Acyclic 1,2-Diamines +6