INX-315, a Selective CDK2 Inhibitor, Induces Cell Cycle Arrest and Senescence in Solid Tumors

Catherine Dietrich, Alec Trub, Antonio Ahn, +14

Cancer Discovery

Marked Global DNA Hypomethylation Is Associated with Constitutive PD-L1 Expression in Melanoma

Aniruddha Chatterjee, Euan J. Rodger, Antonio Ahn, +8

iScience

Genome-wide methylation sequencing of paired primary and metastatic cell lines identifies common DNA methylation changes and a role for EBF3 as a candidate epigenetic driver of melanoma metastasis

Aniruddha Chatterjee, Peter A. Stockwell, Antonio Ahn, +3

Oncotarget

ChromatinEbf3 ExpressionSystems BiologyEbf3 Promoter HypermethylationEpigenetic Change +12

The rs11515 Polymorphism Is More Frequent and Associated With Aggressive Breast Tumors with Increased ANRIL and Decreased p16INK4a Expression

Janice A. Royds, Anna P. Pilbrow, Antonio Ahn, +9

Frontiers in Oncology

A Guide for Designing and Analyzing RNA-Seq Data

Aniruddha Chatterjee, Antonio Ahn, Euan J. Rodger, +2

Methods in molecular biology

Functional GenomicsEngineeringGeneticsRna Structure PredictionComputational Biology +5

The CDKN2A G500 Allele Is More Frequent in GBM Patients with No Defined Telomere Maintenance Mechanism Tumors and Is Associated with Poorer Survival

Janice A. Royds, Shafagh Al Nadaf, Anna Wiles, +10

PLoS ONE

PathologyHigh-grade GliomasCancer BiologyGliomaPrognostic Markers +14

An epigenetic signature of advanced colorectal cancer metastasis

Euan J. Rodger, Grégory Gimenez, Priyadarshana Ajithkumar, +12

iScience

The CD8+ T cell tolerance checkpoint triggers a distinct differentiation state defined by protein translation defects

Willem Van Der Byl, Simone Nüssing, Timothy J. Peters, +25

Immunity

Cell RegulationT-regulatory CellProtein Translation DefectsImmunologyDistinct Differentiation State +6

Transcriptional Reprogramming and Constitutive PD-L1 Expression in Melanoma Are Associated with Dedifferentiation and Activation of Interferon and Tumour Necrosis Factor Signalling Pathways

Antonio Ahn, Euan J. Rodger, Jyoti Motwani, +6

Cancers

Repurposing Melanoma Chemotherapy to Activate Inflammasomes in the Treatment of BRAF/MAPK Inhibitor Resistant Melanoma

Farzana Ahmed, Hsin‐Yi Tseng, Antonio Ahn, +8

Journal of Investigative Dermatology

MedicineMelanomaImmunologyMelanoma ChemotherapyImmune Checkpoint Inhibitor +7