Laura O’Regan - Concepedia

Author

Laura O’Regan

University of Leicester ORCID

Also Known As

Laura O'Regan, Laura O’Regan, O'Regan, Laura

Publications

1.7K

Citations

H-Index

Concepts

All Affiliations

University of Leicester University of Leeds University of Warwick University of Ulsan Institute of Structural and Molecular Biology

About

Laura O’Regan is an author at University of Leicester specializing in cytoskeleton, signal transduction, and cell division.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	2	2	207
2	Cell Biology	2	2	207
3	Natural Sciences	1	1	16
4	Cellular Physiology	1	1	191
5	Immunology	1	1	191

Laura O’Regan

Publications

1.2K

Citations

H-Index

Page 1

	Year	Citations
Mitotic regulation by NIMA-related kinases Laura O’Regan, Joëlle Blot, Andrew M. Fry Cell Division	2007	218
The Nek6 and Nek7 Protein Kinases Are Required for Robust Mitotic Spindle Formation and Cytokinesis Laura O’Regan, Andrew M. Fry Molecular and Cellular Biology Signal TransductionFragile Mitotic SpindlesCell DivisionSignaling PathwayCell Signaling	2009	191
Histone deacetylase (HDAC) 1 and 2 are essential for accurate cell division and the pluripotency of embryonic stem cells Shereen Jamaladdin, Richard D. Kelly, Laura O’Regan, Proceedings of the National Academy of Sciences	2014	166
Crystal structure of EML1 reveals the basis for Hsp90 dependence of oncogenic EML4-ALK by disruption of an atypical β-propeller domain Mark W. Richards, Edward Law, La’Verne P. Rennalls, Proceedings of the National Academy of Sciences	2014	112
Microtubule association of EML proteins and the EML4-ALK variant 3 oncoprotein require an N-terminal trimerization domain Mark W. Richards, Laura O’Regan, Daniel Röth, Biochemical Journal	2015	105
An Autoinhibitory Tyrosine Motif in the Cell-Cycle-Regulated Nek7 Kinase Is Released through Binding of Nek9 Mark W. Richards, Laura O’Regan, Corine Mas-Droux, Molecular Cell	2009	103
Mechanistic basis of Nek7 activation through Nek9 binding and induced dimerization Tamanna Haq, Mark W. Richards, Selena G. Burgess, Nature Communications	2015	62
Hsp72 is targeted to the mitotic spindle by Nek6 to promote K-fiber assembly and mitotic progression Laura O’Regan, Josephina Sampson, Mark W. Richards, The Journal of Cell Biology	2015	53
Mitotic phosphorylation by NEK6 and NEK7 reduces the microtubule affinity of EML4 to promote chromosome congression Rozita Adib, Jessica M. Montgomery, Joseph Atherton, Science Signaling	2019	51
EML4–ALK V3 oncogenic fusion proteins promote microtubule stabilization and accelerated migration through NEK9 and NEK7 Laura O’Regan, Giancarlo Barone, Rozita Adib, Journal of Cell Science	2020	45

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