Seline A. Zwarthoff

Staphylococcal protein A inhibits complement activation by interfering with IgG hexamer formation

Ana Rita Cruz, Maurits A. den Boer, Jürgen Strasser et al. · Proceedings of the National Academy of Sciences · 2021 · 112 citations · Full text

Life Sciences, Immunology, Microbiology +17

Functional Characterization of Alternative and Classical Pathway C3/C5 Convertase Activity and Inhibition Using Purified Models

Seline A. Zwarthoff, Evelien T.M. Berends, Sanne Mol et al. · Frontiers in Immunology · 2018 · 82 citations · Full text

Life Sciences, Cell Biology, Immunology +14

C1q binding to surface-bound IgG is stabilized by C1r ₂ s ₂ proteases

Seline A. Zwarthoff, Kevin Widmer, Annemarie Kuipers et al. · Proceedings of the National Academy of Sciences · 2021 · 60 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

BYON4228 is a pan-allelic antagonistic SIRPα antibody that potentiates destruction of antibody-opsonized tumor cells and lacks binding to SIRPγ on T cells

Mary J. van Helden, Seline A. Zwarthoff, Roel J. Arends et al. · Journal for ImmunoTherapy of Cancer · 2023 · 19 citations · Full text

Medicine, Immunology, Oncology +16

Promoting Fc-Fc interactions between anti-capsular antibodies provides strong immune protection against Streptococcus pneumoniae

Leire Aguinagalde, Maurits A. den Boer, Suzanne M. Castenmiller et al. · eLife · 2023 · 17 citations · Full text

Pharmacy, Immunology, Microbiology +17