Natalie A. Dales

ACE2 X-Ray Structures Reveal a Large Hinge-bending Motion Important for Inhibitor Binding and Catalysis

Paul Towler, Bart L. Staker, Sridhar G. Prasad et al. · Journal of Biological Chemistry · 2004 · 738 citations · Full text

X-ray Crystallography, Engineering, Biochemistry +9

SMN2 splice modulators enhance U1–pre-mRNA association and rescue SMA mice

James Palacino, Susanne E. Swalley, Cheng Song et al. · Nature Chemical Biology · 2015 · 422 citations

Transcriptional Regulation, Genetics, Gene Regulation +7

Substrate-Based Design of the First Class of Angiotensin-Converting Enzyme-Related Carboxypeptidase (ACE2) Inhibitors

Natalie A. Dales, Alexandra E. Gould, James A. Brown et al. · Journal of the American Chemical Society · 2002 · 186 citations · Full text

Selective Ace2 Inhibitors, Medicinal Chemistry, Zinc Metalloprotease +14

Surfactant effects on protein structure examined by electrospray ionization mass spectrometry

R. R. Ogorzalek Loo, Natalie A. Dales, Philip Andrews · Protein Science · 1994 · 184 citations · Full text

Discovery and characterization of a selective IKZF2 glue degrader for cancer immunotherapy

Simone Bonazzi, Eva d’Hennezel, Rohan E. J. Beckwith et al. · Cell chemical biology · 2023 · 135 citations · Full text