Concepedia

Natalie A. Dales

NA

20

Publications

2.3K

Citations

15

H-Index

1994

Active since

Affiliations

Novartis (United States)(Current)

Novartis (Switzerland)

Millennium Engineering and Integration (United States)

Xenon Pharmaceuticals (Canada)

Novartis Institutes for BioMedical Research

Natalie A. Dales is an author at Novartis (United States) specializing in medicine, natural sciences, and biochemistry.

Top concepts

MedicineNatural SciencesBiochemistryPharmacologyDrug DiscoveryMedicinal ChemistryCell BiologyPharmacotherapyGene ExpressionDrug Development

Publications per year

1994–2024

20

Publications

20

ACE2 X-Ray Structures Reveal a Large Hinge-bending Motion Important for Inhibitor Binding and Catalysis

Paul Towler, Bart L. Staker, Sridhar G. Prasad et al. · Journal of Biological Chemistry · 2004 · 738 citations · Full text

X-ray Crystallography, Engineering, Biochemistry +9

SMN2 splice modulators enhance U1–pre-mRNA association and rescue SMA mice

James Palacino, Susanne E. Swalley, Cheng Song et al. · Nature Chemical Biology · 2015 · 422 citations

Transcriptional Regulation, Genetics, Gene Regulation +7

Substrate-Based Design of the First Class of Angiotensin-Converting Enzyme-Related Carboxypeptidase (ACE2) Inhibitors

Natalie A. Dales, Alexandra E. Gould, James A. Brown et al. · Journal of the American Chemical Society · 2002 · 186 citations · Full text

Selective Ace2 Inhibitors, Medicinal Chemistry, Zinc Metalloprotease +14

Surfactant effects on protein structure examined by electrospray ionization mass spectrometry

R. R. Ogorzalek Loo, Natalie A. Dales, Philip Andrews · Protein Science · 1994 · 184 citations · Full text

Discovery and characterization of a selective IKZF2 glue degrader for cancer immunotherapy

Simone Bonazzi, Eva d’Hennezel, Rohan E. J. Beckwith et al. · Cell chemical biology · 2023 · 135 citations · Full text

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