Sean G. Lacoursiere

Age-dependent behavioral and biochemical characterization of single APP knock-in mouse (APPNL-G-F/NL-G-F) model of Alzheimer's disease

Jogender Mehla, Sean G. Lacoursiere, Valérie Lapointe et al. · Neurobiology of Aging · 2018 · 154 citations

Life Sciences, Neurobiology, Neuroscience +16

Gradual Cerebral Hypoperfusion Impairs Fear Conditioning and Object Recognition Learning and Memory in Mice: Potential Roles of Neurodegeneration and Cholinergic Dysfunction

Jogender Mehla, Sean G. Lacoursiere, Emily Stuart et al. · Journal of Alzheimer s Disease · 2017 · 27 citations

Life Sciences, Neurobiology, Neuroscience +17

Dramatic impacts on brain pathology, anxiety, and cognitive function in the knock-in APPNL-G-F mouse model of Alzheimer disease following long-term voluntary exercise

Jogender Mehla, Scott H. Deibel, Hadil Karem et al. · Alzheimer s Research & Therapy · 2022 · 19 citations · Full text

Medicine, Neurobiology, Neuroscience +17

Repeated multi-domain cognitive training prevents cognitive decline, anxiety and amyloid pathology found in a mouse model of Alzheimer disease

Jogender Mehla, Scott H. Deibel, Hadil Karem et al. · Communications Biology · 2023 · 17 citations · Full text

Life Sciences, Neurobiology, Neuroscience +16

Weak-hyperactive hippocampal CA1 neurons in the prodromal stage of Alzheimer's disease in hybrid AppNL-G-F/NL-G-F × Thy1-GCaMP6s+/− mice suggest disrupted plasticity

Samsoon Inayat, Brendan B. McAllister, HaoRan Chang et al. · Neurobiology of Aging · 2023 · 10 citations

Life Sciences, Neurobiology, Neuroscience +14