Loss-of-function mutations in MGME1 impair mtDNA replication and cause multisystemic mitochondrial disease

Cornelia Kornblum, Thomas J. Nicholls, Tobias B. Haack, +22

Nature Genetics

Mitochondrial MyopathyGenome InstabilityMitochondrial FunctionNatural SciencesGenetics +6

Linear mitochondrial DNA is rapidly degraded by components of the replication machinery

Viktoriya Peeva, Daniel Blei, Genevieve Trombly, +10

Nature Communications

Mosaic Deficiency in Mitochondrial Oxidative Metabolism Promotes Cardiac Arrhythmia during Aging

Olivier R. Baris, Stefan Ederer, Johannes Neuhaus, +12

Cell Metabolism

Cardiac MuscleCardiomyopathyHeart FailureMitochondrial FunctionBiochemistry +8

Mitofusin 2 mutations affect mitochondrial function by mitochondrial DNA depletion

Stefan Vielhaber, Grażyna Dębska–Vielhaber, Viktoriya Peeva, +10

Acta Neuropathologica

BiologyMitophagyMitochondrial FunctionNatural SciencesGenetics +7

Linear mtDNA fragments and unusual mtDNA rearrangements associated with pathological deficiency of MGME1 exonuclease

Thomas J. Nicholls, Gábor Zsurka, Viktoriya Peeva, +10

Human Molecular Genetics

GeneticsDna AnalysisMolecular BiologyPathologyMolecular Genetics +17

Mutant desmin substantially perturbs mitochondrial morphology, function and maintenance in skeletal muscle tissue

Lilli Winter, Ilka Wittig, Viktoriya Peeva, +13

Acta Neuropathologica

Muscle FunctionSkeletal Muscle TissueMitochondrial DysfunctionMolecular BiologyCytoskeleton +16

Effects of Korean Red Ginseng (Panax ginseng C.A. Mayer) and Its Isolated Ginsenosides and Polysaccharides on Arterial Stiffness in Healthy Individuals

Elena Jovanovski, Abigail K. Jenkins, António Guerner Dias, +6

American Journal of Hypertension

Neuropathological signs of inflammation correlate with mitochondrial DNA deletions in mesial temporal lobe epilepsy

Elisa Volmering, Pitt Niehusmann, Viktoriya Peeva, +8

Acta Neuropathologica

Neurobiology Of DiseaseNeurological DisorderNeuroanatomyMedicineExperimental Neuropathology +9

Impairment of mitochondrial oxidative phosphorylation in skin fibroblasts of SALS and FALS patients is rescued by in vitro treatment with ROS scavengers

Grażyna Dębska–Vielhaber, Irina Miller, Viktoriya Peeva, +11

Experimental Neurology

Ros ScavengersSclerodermaMitochondrial FunctionBiochemistryLipid Peroxidation +10

Distinct patterns of mitochondrial genome diversity in bonobos (Pan paniscus) and humans

Gábor Zsurka, Tatiana A. Kudina, Viktoriya Peeva, +4

BMC Evolutionary Biology