Jacob A. Van Winkle

Homeostatic interferon-lambda response to bacterial microbiota stimulates preemptive antiviral defense within discrete pockets of intestinal epithelium

Jacob A. Van Winkle, Stefan T. Peterson, Elizabeth A. Kennedy et al. · eLife · 2022 · 55 citations · Full text

Selective Interferon Responses of Intestinal Epithelial Cells Minimize Tumor Necrosis Factor Alpha Cytotoxicity

Jacob A. Van Winkle, David A. Constant, Lena Li et al. · Journal of Virology · 2020 · 42 citations · Full text

Persistence of Systemic Murine Norovirus Is Maintained by Inflammatory Recruitment of Susceptible Myeloid Cells

Jacob A. Van Winkle, Bridget A. Robinson, A. Mack Peters et al. · Cell Host & Microbe · 2018 · 36 citations · Full text

Inflammation, Viral Persistence, Viral Pathogenesis +8

Caspase-mediated cleavage of murine norovirus NS1/2 potentiates apoptosis and is required for persistent infection of intestinal epithelial cells

Bridget A. Robinson, Jacob A. Van Winkle, Broc T. McCune et al. · PLoS Pathogens · 2019 · 33 citations · Full text

Human Norovirus, Apoptosis, Viral Pathogenesis +17

Autophagy promotes efficient T cell responses to restrict high-dose Mycobacterium tuberculosis infection in mice

Siwei Feng, Michael E. McNehlan, Rachel L. Kinsella et al. · Nature Microbiology · 2024 · 32 citations

Inflammation, Cell Autophagy, Adaptive Immune System +7