Karen Legler

Cancer Cell-Autonomous TRAIL-R Signaling Promotes KRAS-Driven Cancer Progression, Invasion, and Metastasis

Silvia von Karstedt, Annalisa Conti, Max Nobis et al. · Cancer Cell · 2015 · 190 citations · Full text

Cancer Research, Signal Transduction, Signaling Pathway +10

Central Inhibition of IKKβ/NF-κB Signaling Attenuates High-Fat Diet–Induced Obesity and Glucose Intolerance

Jonas Benzler, Goutham K. Ganjam, Dominik Pretz et al. · Diabetes · 2015 · 128 citations

Inhibition of IL‐6 signaling significantly reduces primary tumor growth and recurrencies in orthotopic xenograft models of pancreatic cancer

Freya A. Goumas, Reinhild Holmer, Jan‐Hendrik Egberts et al. · International Journal of Cancer · 2015 · 109 citations

Immunology, Immunoediting, Cell Proliferation +18

Mast cells decrease efficacy of anti-angiogenic therapy by secreting matrix-degrading granzyme B

Mark Wroblewski, R. Bauer, Miguel Cubas Córdova et al. · Nature Communications · 2017 · 74 citations · Full text

Reduced mannosidase MAN1A1 expression leads to aberrant N-glycosylation and impaired survival in breast cancer

Karen Legler, Ricarda Rosprim, Tosca Karius et al. · British Journal of Cancer · 2018 · 67 citations · Full text