Runx2 Is a Common Target of Transforming Growth Factor β1 and Bone Morphogenetic Protein 2, and Cooperation between Runx2 and Smad5 Induces Osteoblast-Specific Gene Expression in the Pluripotent Mesenchymal Precursor Cell Line C2C12

Kyeong‐Sook Lee, Hyun‐Jung Kim, Qinglin Li, +8

Molecular and Cellular Biology

Dlx5 Specifically Regulates Runx2 Type II Expression by Binding to Homeodomain-response Elements in the Runx2 Distal Promoter

Mi‐Hye Lee, Youn Jeong Kim, Won‐Joon Yoon, +10

Journal of Biological Chemistry

SclerostinGeneticsCellular PhysiologyRunx2 Type IiTranscriptional Regulation +14

RUNX3 Suppresses Gastric Epithelial Cell Growth by Inducing <i>p21</i>^<i>WAF1</i>^/<i>Cip1</i> Expression in Cooperation with Transforming Growth Factor β-Activated SMAD

Xin‐Zi Chi, Jeung-Ook Yang, Kwang-Youl Lee, +11

Molecular and Cellular Biology

PathologyCell ProliferationCell GrowthCancer BiologyCellular Physiology +15

The RUNX3 Tumor Suppressor Upregulates Bim in Gastric Epithelial Cells Undergoing Transforming Growth Factorβ-Induced Apoptosis

Takashi Yano, Kosei Ito, Hiroshi Fukamachi, +8

Molecular and Cellular Biology

Cancer ResearchHuman Bim PromoterProapoptotic Gene BimGastrointestinal OncologyMedicine +10

Runx3 Inactivation Is a Crucial Early Event in the Development of Lung Adenocarcinoma

You‐Soub Lee, Jung-Won Lee, Juwon Jang, +14

Cancer Cell

Tumor BiologyOncogenic AgentMedicineLung AdenocarcinomaPathology +9

RUNX3 regulates cell cycle-dependent chromatin dynamics by functioning as a pioneer factor of the restriction-point

Jung-Won Lee, Da-Mi Kim, Juwon Jang, +8

Nature Communications

Runt-Related Transcription Factor RUNX3 Is a Target of MDM2-Mediated Ubiquitination

Xin‐Zi Chi, Jiyeon Kim, Yong‐Hee Lee, +10

Cancer Research

Radiation OncologyActivated RasSignaling PathwayCell RegulationMedicine +13

Src Kinase Phosphorylates RUNX3 at Tyrosine Residues and Localizes the Protein in the Cytoplasm

Yun‐Mi Goh, Senthilkumar Cinghu, Eileen Tan Hwee Hong, +10

Journal of Biological Chemistry

Jab1/CSN5 induces the cytoplasmic localization and degradation of RUNX3

Jang‐Hyun Kim, Joong‐Kook Choi, Senthilkumar Cinghu, +8

Journal of Cellular Biochemistry

Dna MethylationMolecular BiologyCytoskeletonCytoplasmic LocalizationCancer Biology +15