MIBiG 3.0: a community-driven effort to annotate experimentally validated biosynthetic gene clusters

Barbara R. Terlouw, Kai Blin, Jorge C. Navarro-Muñoz, +78

Nucleic Acids Research

Biosynthetic Gene ClustersEngineeringGeneticsMolecular BiologyMibig 2.0 +23

Expansion of RiPP biosynthetic space through integration of pan-genomics and machine learning uncovers a novel class of lanthipeptides

Alexander Kloosterman, Peter Cimermančič, Somayah S. Elsayed, +6

PLoS Biology

Modified PeptidesEngineeringStructural BioinformaticsBiomolecular Structure PredictionMolecular Biology +24

A community resource for paired genomic and metabolomic data mining

Michelle Schorn, Stefan Verhoeven, Lars Ridder, +107

Nature Chemical Biology

Antibiotic production in <i>Streptomyces</i> is organized by a division of labor through terminal genomic differentiation

Zheren Zhang, Chao Du, Frédérique de Barsy, +6

Science Advances

Metabolomics-Driven Discovery of a Prenylated Isatin Antibiotic Produced by<i>Streptomyces</i>Species MBT28

Changsheng Wu, Chao Du, Jacob Gubbens, +2

Journal of Natural Products

EngineeringMetabolomic ProfilingMolecular BiologyNovel AntibioticsDrug Resistance +20

Expression of a Na+/H+ antiporter RtNHX1 from a recretohalophyte Reaumuria trigyna improved salt tolerance of transgenic Arabidopsis thaliana

Ningning Li, Xue Wang, Binjie Ma, +3

Journal of Plant Physiology

BiologyPlant Molecular BiologyBiosynthesisEngineeringAbiotic Stress +9

The Reaumuria trigyna transcription factor RtWRKY1 confers tolerance to salt stress in transgenic Arabidopsis

Chao Du, Pingping Zhao, Huirong Zhang, +3

Journal of Plant Physiology

BiologyPlant Molecular BiologyPlant StressAbiotic StressNatural Sciences +6

iTRAQ-Based Proteomic Analysis of the Metabolism Mechanism Associated with Silicon Response in the Marine Diatom <i>Thalassiosira pseudonana</i>

Chao Du, Junrong Liang, Dandan Chen, +6

Journal of Proteome Research

Discovery of <i>C</i>-Glycosylpyranonaphthoquinones in <i>Streptomyces</i> sp. MBT76 by a Combined NMR-Based Metabolomics and Bioinformatics Workflow

Changsheng Wu, Chao Du, Koji Ichinose, +2

Journal of Natural Products

EngineeringGlycobiologyMetabolomic ProfilingMolecular BiologySecondary Metabolite +16

Enzyme-Constrained Models and Omics Analysis of <i>Streptomyces coelicolor</i> Reveal Metabolic Changes that Enhance Heterologous Production.

Snorre Sulheim, Tjaša Kumelj, Dino van Dissel, +7

PubMed