Nels Hamacher

Structure of FcγRI in complex with Fc reveals the importance of glycan recognition for high-affinity IgG binding

Jinghua Lu, Jonathan Chu, Zhongcheng Zou et al. · Proceedings of the National Academy of Sciences · 2015 · 146 citations · Full text

Life Sciences, Biochemistry, Immunology +17

B-lymphocyte stimulator/a proliferation-inducing ligand heterotrimers are elevated in the sera of patients with autoimmune disease and are neutralized by atacicept and B-cell maturation antigen-immunoglobulin

Stacey R. Dillon, Brandon Harder, Kenneth B. Lewis et al. · Arthritis Research & Therapy · 2010 · 100 citations · Full text

Life Sciences, Immunology, Autoimmunity +12

Crystal Structure of Fcγ Receptor I and Its Implication in High Affinity γ-Immunoglobulin Binding

Jinghua Lu, Jeff L. Ellsworth, Nels Hamacher et al. · Journal of Biological Chemistry · 2011 · 88 citations · Full text

Life Sciences, Biology, Immunology +16

Mapping the Energetic Epitope of an Antibody/Interleukin-23 Interaction with Hydrogen/Deuterium Exchange, Fast Photochemical Oxidation of Proteins Mass Spectrometry, and Alanine Shave Mutagenesis

Jing Li, Hui Wei, Stanley R. Krystek et al. · Analytical Chemistry · 2017 · 86 citations · Full text

Life Sciences, Biochemistry, Immunology +17

Engineering of stable bispecific antibodies targeting IL-17A and IL-23

Robert L. Mabry, Katherine E. Lewis, Margaret Moore et al. · Protein Engineering Design and Selection · 2009 · 58 citations

Pharmacy, Biotechnology, Immunology +17