RNA Targeting by the Type III-A CRISPR-Cas Csm Complex of Thermus thermophilus

Raymond H.J. Staals, Yifan Zhu, David W. Taylor, +18

Molecular Cell

EngineeringThermus ThermophilusRna BiologyGenetic EngineeringMolecular Biology +7

A Novel Human CC Chemokine, Eotaxin-3, Which Is Expressed in IL-4-Stimulated Vascular Endothelial Cells, Exhibits Potent Activity Toward Eosinophils

Akeo Shinkai, Hajime Yoshisue, Masamichi Koike, +10

The Journal of Immunology

Structure and Activity of the RNA-Targeting Type III-B CRISPR-Cas Complex of Thermus thermophilus

Raymond H.J. Staals, Yoshihiro Agari, Saori Maki-Yonekura, +15

Molecular Cell

Thermus ThermophilusRna Structure PredictionRna BiologyMolecular BiologyGene Editing +5

Mapping of the Sites Involved in Ligand Association and Dissociation at the Extracellular Domain of the Kinase Insert Domain-containing Receptor for Vascular Endothelial Growth Factor

Akeo Shinkai, Mikito Ito, Hideharu Anazawa, +3

Journal of Biological Chemistry

Structures of the CRISPR-Cmr complex reveal mode of RNA target positioning

David W. Taylor, Yifan Zhu, Raymond H.J. Staals, +5

Science

Transcription Profile of Thermus thermophilus CRISPR Systems after Phage Infection

Yoshihiro Agari, Keiko Sakamoto, Masatada Tamakoshi, +3

Journal of Molecular Biology

BacteriophageMolecular BiologyTranscription ProfileGenome EditingMicrobiology +3

SecA, an essential component of the secretory machinery of Escherichiacoli, exists as homodimer

Mitsuru Akita, Akeo Shinkai, Shin-ichi Matsuyama, +1

Biochemical and Biophysical Research Communications

BiologySecretory MachineryProtein SecretionNatural SciencesVirulence Factor +8

Significant expression of vascular endothelial growth factor/vascular permeability factor in mouse ascites tumors.

Jin Luo, Sachiko Yamaguchi, Akeo Shinkai, +2

PubMed

Vegf ProductionImmunologyPathologyActive VegfTumor Biology +14

The conformation of SecA, as revealed by its protease sensitivity, is altered upon interaction with ATP, presecretory proteins, everted membrane vesicles, and phospholipids.

Akeo Shinkai, Lúcia Helena Innocentini Mei, Haruhiko Tokuda, +1

Journal of Biological Chemistry

Proteinlipid InteractionProtein SecretionMolecular BiologyEscherichia ColiCellular Physiology +16

SCOPE enables type III CRISPR-Cas diagnostics using flexible targeting and stringent CARF ribonuclease activation

Jurre A. Steens, Yifan Zhu, David W. Taylor, +10

Nature Communications

EngineeringGeneticsImmunologyMolecular BiologyTarget Rna +14