Improving baculovirus production at high cell density through manipulation of energy metabolism

Nuno Carinhas, Vicente Bernal, Francisca Monteiro, +3

Metabolic Engineering

Viral ReplicationEnergy MetabolismEngineeringHigh Cell DensityBiotechnology +6

Measuring glycolytic flux in single yeast cells with an orthogonal synthetic biosensor

Francisca Monteiro, Georg Hubmann, Vakil Takhaveev, +8

Molecular Systems Biology

Toward system-level understanding of baculovirus–host cell interactions: from molecular fundamental studies to large-scale proteomics approaches

Francisca Monteiro, Nuno Carinhas, Manuel J.T. Carrondo, +2

Frontiers in Microbiology

Molecular BiologyToward System-level UnderstandingInsect CellsProteomicsViral Genetics +15

Targeted supplementation design for improved production and quality of enveloped viral particles in insect cell-baculovirus expression system

Francisca Monteiro, Vicente Bernal, Maxime Chaillet, +2

Journal of Biotechnology

Viral ReplicationInsect VirusEnveloped Viral ParticlesSynthetic VirologyImmunology +5

Metabolic profiling of insect cell lines: Unveiling cell line determinants behind system's productivity

Francisca Monteiro, Vicente Bernal, Xavier Saelens, +5

Biotechnology and Bioengineering

EngineeringMetabolic ModelMetabolic NetworkBiosynthesisBioenergetics +18

An integrated analysis of enzyme activities, cofactor pools and metabolic fluxes in baculovirus-infected Spodoptera frugiperda Sf9 cells

Vicente Bernal, Francisca Monteiro, Nuno Carinhas, +2

Journal of Biotechnology

Integrated AnalysisBiochemistryInsect VirusBioenergeticsNatural Sciences +7

Bioorthogonal Strategy for Bioprocessing of Specific-Site-Functionalized Enveloped Influenza-Virus-Like Particles

Sofia B. Carvalho, João M. Freire, Mafalda G. Moleirinho, +7

Bioconjugate Chemistry

BiomanufacturingVlp ProductionEngineeringBiochemistrySynthetic Virology +13

The role of host cell physiology in the productivity of the baculovirus‐insect cell system: Fluxome analysis of <i>Trichoplusia ni</i> and <i>Spodoptera frugiperda</i> cell lines

Francisca Monteiro, Vicente Bernal, Paula M. Alves

Biotechnology and Bioengineering

The Perfect Condition for the Rising of Superbugs: Person-to-Person Contact and Antibiotic Use Are the Key Factors Responsible for the Positive Correlation between Antibiotic Resistance Gene Diversity and Virulence Gene Diversity in Human Metagenomes

Célia P. F. Domingues, João S. Rebelo, Joël Pothier, +3

Antibiotics

GeneticsAntibiotic ResistanceBacterial PathogensVirulence GenesDrug Resistance +14

Improvement of lentiviral transfer vectors using cis-acting regulatory elements for increased gene expression

Gonçalo Real, Francisca Monteiro, Christa Burger, +1

Applied Microbiology and Biotechnology

Human RetrovirusLentiviral Transfer VectorsImmunologyCis-acting Regulatory ElementsAntiviral Therapy +9