Alexandre Beautrait

A new inhibitor of the β-arrestin/AP2 endocytic complex reveals interplay between GPCR internalization and signalling

Alexandre Beautrait, Justine S. Paradis, Brandon Zimmerman et al. · Nature Communications · 2017 · 213 citations · Full text

Differential β-Arrestin–Dependent Conformational Signaling and Cellular Responses Revealed by Angiotensin Analogs

Brandon Zimmerman, Alexandre Beautrait, Benjamin Aguila et al. · Science Signaling · 2012 · 163 citations

Cellular Responses Revealed, Cellular Physiology, Molecular Pharmacology +19

Enhancing Hit Discovery in Virtual Screening through Absolute Protein–Ligand Binding Free-Energy Calculations

Wei Chen, Di Cui, Steven V. Jerome et al. · Journal of Chemical Information and Modeling · 2023 · 110 citations

Receptor sequestration in response to β-arrestin-2 phosphorylation by ERK1/2 governs steady-state levels of GPCR cell-surface expression

Justine S. Paradis, Stevenson Ly, Élodie Blondel-Tepaz et al. · Proceedings of the National Academy of Sciences · 2015 · 48 citations · Full text

Quantifying biased signaling in GPCRs using BRET-based biosensors

Yoon Namkung, Olivier Radresa, Sylvain Armando et al. · Methods · 2015 · 41 citations

Signal Transduction, Biomolecular Tool, Bioanalysis +4