FTO Plays an Oncogenic Role in Acute Myeloid Leukemia as a N 6 -Methyladenosine RNA Demethylase

Zejuan Li, Hengyou Weng, Rui Su, +26

Cancer Cell

N 6ChromatinNatural SciencesAcute Myeloid LeukemiaMixed-phenotype Acute Leukemia +8

<i>TET1</i> plays an essential oncogenic role in <i>MLL</i> -rearranged leukemia

Hao Huang, Xi Jiang, Zejuan Li, +26

Proceedings of the National Academy of Sciences

Essential Oncogenic RoleChromatinHematological MalignancySystems BiologyMixed-phenotype Acute Leukemia +13

Blockade of miR-150 Maturation by MLL-Fusion/MYC/LIN-28 Is Required for MLL-Associated Leukemia

Xi Jiang, Hao Huang, Zejuan Li, +25

Cancer Cell

Hematological MalignancyMir-150 MaturationMedicineImmunologyMll-associated Leukemia +8

PBX3 is an important cofactor of HOXA9 in leukemogenesis

Zejuan Li, Zhiyu Zhang, Yuanyuan Li, +21

Blood

miR-196b directly targets both HOXA9/MEIS1 oncogenes and FAS tumour suppressor in MLL-rearranged leukaemia

Zejuan Li, Hao Huang, Ping Chen, +27

Nature Communications

Cancer ResearchMll-rearranged LeukaemiaCancer GenomicsHoxa9/meis1 OncogenesCell Biology +6

Up-regulation of a HOXA-PBX3 homeobox-gene signature following down-regulation of miR-181 is associated with adverse prognosis in patients with cytogenetically abnormal AML

Zejuan Li, Hao Huang, Yuanyuan Li, +27

Blood

miR-22 has a potent anti-tumour role with therapeutic potential in acute myeloid leukaemia

Xi Jiang, Chao Hu, Stephen Arnovitz, +27

Nature Communications

Overexpression and knockout of miR-126 both promote leukemogenesis

Zejuan Li, Ping Chen, Rui Su, +22

Blood

miR-9 is an essential oncogenic microRNA specifically overexpressed in <i>mixed lineage leukemia</i> –rearranged leukemia

Ping Chen, Colles Price, Zejuan Li, +20

Proceedings of the National Academy of Sciences

miR-495 is a tumor-suppressor microRNA down-regulated in <i>MLL</i> -rearranged leukemia

Xi Jiang, Hao Huang, Zejuan Li, +19

Proceedings of the National Academy of Sciences