John M. Sedivy

Requirement for p53 and p21 to Sustain G ₂ Arrest After DNA Damage

Fred Bunz, Annie Dutriaux, Christoph Lengauer et al. · Science · 1998 · 2.8K citations

Mitochondrial DNA Mutations, Oxidative Stress, and Apoptosis in Mammalian Aging

Gregory C. Kujoth, Asimina Hiona, Thomas D. Pugh et al. · Science · 2005 · 2.1K citations

Aging, Mitochondrial Function, Mitochondrial Dynamic +12

Telomere Shortening Triggers Senescence of Human Cells through a Pathway Involving ATM, p53, and p21CIP1, but Not p16INK4a

Utz Herbig, Wendy A. Jobling, Benjamin P.C. Chen et al. · Molecular Cell · 2004 · 1.3K citations · Full text

Genome Instability, Aging, Human Cells +6

L1 drives IFN in senescent cells and promotes age-associated inflammation

Marco De Cecco, Takahiro Ito, Anna P. Petrashen et al. · Nature · 2019 · 1.2K citations

Inflammation, Cytokine, Immunology +8

Cellular Senescence in Aging Primates

Utz Herbig, Mark Ferreira, Laura Condel et al. · Science · 2006 · 1.1K citations

Lifespan Extension, Replicative Senescence, Aging +12