Phagosomal removal of fungal melanin reprograms macrophage metabolism to promote antifungal immunity

Samuel M. Gonçalves, Cláudio Duarte‐Oliveira, Cláudia F. Campos, +31

Nature Communications

Type I IFN Inhibits Alternative Macrophage Activation during <i>Mycobacterium tuberculosis</i> Infection and Leads to Enhanced Protection in the Absence of IFN-γ Signaling

Lúcia Moreira-Teixeira, Jeremy Sousa, Finlay W. McNab, +11

The Journal of Immunology

Neutralizing Anti-Granulocyte Macrophage-Colony Stimulating Factor Autoantibodies Recognize Post-Translational Glycosylations on Granulocyte Macrophage-Colony Stimulating Factor Years Before Diagnosis and Predict Complicated Crohn’s Disease

Arthur Mortha, Romain Remark, Diane M. Del Valle, +32

Gastroenterology

<i>Akkermansia muciniphila</i> and <i>Parabacteroides distasonis</i> synergistically protect from colitis by promoting ILC3 in the gut

Joana Gaifem, Ana Mendes‐Frias, Mathis Wolter, +12

mBio

Altered IgG glycosylation at COVID‐19 diagnosis predicts disease severity

Manuel M. Vicente, Inês Alves, Joana Gaifem, +15

European Journal of Immunology

Clinical ImmunologyImmunodeficienciesImmunologyGlycobiologyImmunodominance +20

A unique serum IgG glycosylation signature predicts development of Crohn’s disease and is associated with pathogenic antibodies to mannose glycan

Joana Gaifem, Cláudia S. Rodrigues, Francesca Petralia, +18

Nature Immunology

IL-17A Promotes Intracellular Growth of Mycobacterium by Inhibiting Apoptosis of Infected Macrophages

Andrea Cruz, Paula Ludovico, Egídio Torrado, +9

Frontiers in Immunology

InflammationCytokinePulmonary TuberculosisInfected MacrophagesHost Response +13

Bioprospecting Portuguese Atlantic coast cyanobacteria for bioactive secondary metabolites reveals untapped chemodiversity

Ângela Brito, Joana Gaifem, Vítor Ramos, +6

Algal Research

BiologyMarine BiotechnologyEngineeringSecondary MetaboliteMicrobiology +5

Sphingolipid signalling mediates mitochondrial dysfunctions and reduced chronological lifespan in the yeast model of <scp>N</scp>iemann‐<scp>P</scp>ick type <scp>C</scp>1

Rita Vilaça, Elísio Silva, André Nadais, +6

Molecular Microbiology

Yeast ModelLipid PeroxidationYeast CellsOxidative StressMammalian Npc1 +17

The influence of surface modified poly(<scp>l</scp>-lactic acid) films on the differentiation of human monocytes into macrophages

Clara R. Correia, Joana Gaifem, Mariana B. Oliveira, +2

Biomaterials Science