B. Gayani K. Perera

Allosteric Inhibition of the IRE1α RNase Preserves Cell Viability and Function during Endoplasmic Reticulum Stress

Rajarshi Ghosh, Likun Wang, Eric S. Wang et al. · Cell · 2014 · 473 citations · Full text

Reductive Stress, Allosteric Inhibition, Molecular Regulation +9

Divergent allosteric control of the IRE1α endoribonuclease using kinase inhibitors

Likun Wang, B. Gayani K. Perera, Sanjay B. Hari et al. · Nature Chemical Biology · 2012 · 189 citations · Full text

Signal Transduction, Biochemistry, Natural Sciences +5

Discovery of Potent and Selective Inhibitors of CDPK1 from <i>C. parvum</i> and <i>T. gondii</i>

Ryan C. Murphy, Kayode K. Ojo, E.T. Larson et al. · ACS Medicinal Chemistry Letters · 2010 · 138 citations · Full text

Pharmaceutical Science, Drug Target, Immunology +22

Development of <i>Toxoplasma gondii</i> Calcium-Dependent Protein Kinase 1 (<i>Tg</i>CDPK1) Inhibitors with Potent Anti-<i>Toxoplasma</i> Activity

Steven M. Johnson, Ryan C. Murphy, Jennifer A. Geiger et al. · Journal of Medicinal Chemistry · 2012 · 113 citations · Full text

Signal Transduction, Parasitic Protozoa, Medicine +12

Multiple Determinants for Selective Inhibition of Apicomplexan Calcium-Dependent Protein Kinase CDPK1

E.T. Larson, Kayode K. Ojo, Ryan C. Murphy et al. · Journal of Medicinal Chemistry · 2012 · 70 citations · Full text

Bioorganic Chemistry, Molecular Biology, Cryptosporidium Parvum +20