Jimmy A. Blair

Escape from HER-family tyrosine kinase inhibitor therapy by the kinase-inactive HER3

Natalia Sergina, Megan Rausch, Donghui Wang et al. · Nature · 2007 · 968 citations · Full text

Signal Transduction, Kinase-inactive Her3, Medicine +7

Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases

Beth Apsel, Jimmy A. Blair, Beatriz González et al. · Nature Chemical Biology · 2008 · 436 citations · Full text

Drug Target, Drug Targeting, Biochemistry +10

Structure-guided development of affinity probes for tyrosine kinases using chemical genetics

Jimmy A. Blair, Daniel Rauh, Charles Kung et al. · Nature Chemical Biology · 2007 · 201 citations · Full text

Chemical Biology, Chemical Genetics, Drug Target +12

Resiliency and Vulnerability in the HER2-HER3 Tumorigenic Driver

Dhara N. Amin, Natalia Sergina, Deepika Ahuja et al. · Science Translational Medicine · 2010 · 184 citations · Full text

Cell Fate Regulation Governed by a Repurposed Bacterial Histidine Kinase

W. Seth Childers, Qingping Xu, Thomas H. Mann et al. · PLoS Biology · 2014 · 71 citations · Full text

Molecular Regulation, Cell Fate Regulation, Molecular Biology +19