Karyotype engineering by chromosome fusion leads to reproductive isolation in yeast

Jingchuan Luo, Xiaoji Sun, Brendan P. Cormack, +1

Nature

Karyotype ImagingChromatinKaryotype EngineeringCytogeneticsHybridization +11

LINE-1 protein localization and functional dynamics during the cell cycle

Paolo Mita, Aleksandra Wudzinska, Xiaoji Sun, +9

eLife

Transcription dynamically patterns the meiotic chromosome-axis interface

Xiaoji Sun, Lingzhi Huang, Tovah E. Markowitz, +4

eLife

GeneticsChromosome FoldingGenomic MechanismMolecular BiologyEpigenetics +14

BRCA1 and S phase DNA repair pathways restrict LINE-1 retrotransposition in human cells

Paolo Mita, Xiaoji Sun, David Fenyö, +8

Nature Structural & Molecular Biology

ChromatinGenome InstabilityCell RegulationHuman CellsGenetics +7

Transcription factor profiling reveals molecular choreography and key regulators of human retrotransposon expression

Xiaoji Sun, Xuya Wang, Zuojian Tang, +6

Proceedings of the National Academy of Sciences

Low escape-rate genome safeguards with minimal molecular perturbation of<i>Saccharomyces cerevisiae</i>

Neta Agmon, Zuojian Tang, Kun Yang, +14

Proceedings of the National Academy of Sciences

Topoisomerases Modulate the Timing of Meiotic DNA Breakage and Chromosome Morphogenesis in <i>Saccharomyces cerevisiae</i>

Jonna Heldrich, Xiaoji Sun, Luís A. Vale-Silva, +2

Genetics

Manipulating the 3D organization of the largest synthetic yeast chromosome

Weimin Zhang, Luciana Lazar‐Stefanita, Hitoyoshi Yamashita, +55

Molecular Cell

Synthetic chromosome fusion: Effects on mitotic and meiotic genome structure and function

Jingchuan Luo, Luís A. Vale-Silva, Adhithi R. Raghavan, +14

Cell Genomics

Application of counter-selectable marker PIGA in engineering designer deletion cell lines and characterization of CRISPR deletion efficiency

Donghui Li, Xiaoji Sun, Fangzhou Yu, +3

Nucleic Acids Research

EngineeringGeneticsGenomicsCrispr Deletion EfficiencyCrispr/cas9 System +19