Coronary Atherosclerosis Is Associated With Macrophage Polarization in Epicardial Adipose Tissue

Yoichiro Hirata, Minoru Tabata, Hirotsugu Kurobe, +10

Journal of the American College of Cardiology

InflammationMetabolic SyndromeVascular DiseaseCardiovascular DiseaseMacrophage Polarization +13

CCR7-Dependent Cortex-to-Medulla Migration of Positively Selected Thymocytes Is Essential for Establishing Central Tolerance

Hirotsugu Kurobe, Cunlan Liu, Tomoo Ueno, +9

Immunity

Positively Selected ThymocytesCentral ToleranceCcr7-dependent Cortex-to-medulla MigrationImmunologySelf-tolerance +8

Epicardial Adipose Tissue Volume and Adipocytokine Imbalance Are Strongly Linked to Human Coronary Atherosclerosis

Michio Shimabukuro, Yoichiro Hirata, Minoru Tabata, +8

Arteriosclerosis Thrombosis and Vascular Biology

Enhanced Inflammation in Epicardial Fat in Patients With Coronary Artery Disease

Yoichiro Hirata, Hirotsugu Kurobe, Masashi Akaike, +7

International Heart Journal

Vascular DiseaseImmunologyPathologyCoronary Artery DiseaseInflammation +20

Well-organized neointima of large-pore poly(l-lactic acid) vascular graft coated with poly(l-lactic-co-ε-caprolactone) prevents calcific deposition compared to small-pore electrospun poly(l-lactic acid) graft in a mouse aortic implantation model

Shuhei Tara, Hirotsugu Kurobe, Kevin A. Rocco, +6

Atherosclerosis

Tissue EngineeringRegenerative MedicineVascular Tissue EngineeringEngineeringWell-organized Neointima +10

HMGB1 plays a critical role in vascular inflammation and lesion formation via toll-like receptor 9

Yoichiro Hirata, Hirotsugu Kurobe, Mayuko Higashida, +6

Atherosclerosis

InflammationCytokineToll-like Receptor 9Vascular InflammationImmunology +10

Evaluation of remodeling process in small-diameter cell-free tissue-engineered arterial graft

Shuhei Tara, Hirotsugu Kurobe, Mark W. Maxfield, +5

Journal of Vascular Surgery

Regenerative MedicineTissue EngineeringVascular Tissue EngineeringVascular GraftsEngineering +10

Development of Small Diameter Nanofiber Tissue Engineered Arterial Grafts

Hirotsugu Kurobe, Mark W. Maxfield, Shuhei Tara, +9

PLoS ONE

Telmisartan ameliorates insulin sensitivity by activating the AMPK/SIRT1 pathway in skeletal muscle of obese db/db mice

Asuka Shiota, Michio Shimabukuro, Daiju Fukuda, +10

Cardiovascular Diabetology

Gender disparities in the association between epicardial adipose tissue volume and coronary atherosclerosis: A 3-dimensional cardiac computed tomography imaging study in Japanese subjects

Munkhbaatar Dagvasumberel, Michio Shimabukuro, Takeshi Nishiuchi, +18

Cardiovascular Diabetology