Breakage and drying behaviour of granules in a continuous fluid bed dryer: Influence of process parameters and wet granule transfer

Fien De Leersnyder, Valérie Vanhoorne, H. Bekaert, +12

European Journal of Pharmaceutical Sciences

EngineeringProcess ParametersDesiccationContinuous FluidCivil Engineering +5

Dynamic Flowsheet Model Development and Sensitivity Analysis of a Continuous Pharmaceutical Tablet Manufacturing Process Using the Wet Granulation Route

Nirupaplava Metta, Michaël Ghijs, Elisabeth Schäfer, +8

Processes

EngineeringIndustrial EngineeringMechanical EngineeringProcess DevelopmentSimulation +18

Can filaments, pellets and powder be used as feedstock to produce highly drug-loaded ethylene-vinyl acetate 3D printed tablets using extrusion-based additive manufacturing?

Aseel Samaro, Bahaa Shaqour, Niloofar Moazami Goudarzi, +8

International Journal of Pharmaceutics

Materials ScienceBiomanufacturingExtrusion-based Additive ManufacturingProcessing And ManufacturingMedicine +2

Model development and prediction of particle size distribution, density and friability of a comilling operation in a continuous pharmaceutical manufacturing process

Nirupaplava Metta, Maxim Verstraeten, Michaël Ghijs, +9

International Journal of Pharmaceutics

Particle Size DistributionEngineeringProcess ControlPopulation Balance ModelingParticle Technology +5

The Influence of Equipment Design and Process Parameters on Granule Breakage in a Semi-Continuous Fluid Bed Dryer after Continuous Twin-Screw Wet Granulation

Alexander Ryckaert, Michaël Ghijs, Christoph Portier, +4

Pharmaceutics

Modeling of Semicontinuous Fluid Bed Drying of Pharmaceutical Granules With Respect to Granule Size

Michaël Ghijs, Elisabeth Schäfer, Ashish Kumar, +6

Journal of Pharmaceutical Sciences

EngineeringDesiccationLiquid-liquid FlowFluid MechanicsMechanical Engineering +6

Analysis of the effect of formulation properties and process parameters on granule formation in twin-screw wet granulation

Michiel Peeters, Ana Alejandra Barrera Jiménez, Kensaku Matsunami, +7

International Journal of Pharmaceutics

Materials ScienceEngineeringMechanical EngineeringGranule FormationTwin-screw Wet Granulation +8

The Fitness–Fatigue Model: What’s in the Numbers?

Kobe Vermeire, Michaël Ghijs, Jan Bourgois, +1

International Journal of Sports Physiology and Performance

Mechanistic modeling of semicontinuous fluidized bed drying of pharmaceutical granules by incorporating single particle and bulk drying kinetics

Tuur Vandeputte, Michaël Ghijs, Daan Van Hauwermeiren, +5

International Journal of Pharmaceutics

Rheological Constitutive EquationEngineeringDesiccationFluid MechanicsMechanical Engineering +7

Two-dimensional moisture content and size measurement of pharmaceutical granules after fluid bed drying using near-infrared chemical imaging

Michaël Ghijs, Brecht Vanbillemont, Niels Nicolaï, +2

International Journal of Pharmaceutics