Concepedia

Katie J. Aldred

KJ

Statistics

Publications

8

Citations

542

H-Index

8

Active since

2009

Affiliations

University of Iowa(Current)

Vanderbilt University

University of Alabama at Birmingham

VA Tennessee Valley Healthcare System

University of Evansville

Katie J. Aldred is an author at University of Iowa specializing in natural sciences, medicine, and antimicrobial drug discovery.

Top concepts

Publications per year

2009–2016

8

Publications

8

Topoisomerase IV-quinolone interactions are mediated through a water-metal ion bridge: mechanistic basis of quinolone resistance

Katie J. Aldred, Sylvia A. McPherson, Charles L. Turnbough et al. · Nucleic Acids Research · 2013 · 170 citations · Full text

Fluoroquinolone interactions with <i>Mycobacterium tuberculosis</i> gyrase: Enhancing drug activity against wild-type and resistant gyrase

Katie J. Aldred, Tim R. Blower, Robert J. Kerns et al. · Proceedings of the National Academy of Sciences · 2016 · 98 citations · Full text

Drug Interactions with <i>Bacillus anthracis</i> Topoisomerase IV: Biochemical Basis for Quinolone Action and Resistance

Katie J. Aldred, Sylvia A. McPherson, Pengfei Wang et al. · Biochemistry · 2011 · 89 citations

, , +24

Overcoming Target-Mediated Quinolone Resistance in Topoisomerase IV by Introducing Metal-Ion-Independent Drug–Enzyme Interactions

Katie J. Aldred, Heidi A. Schwanz, Gangqin Li et al. · ACS Chemical Biology · 2013 · 66 citations · Full text

Role of the Water–Metal Ion Bridge in Mediating Interactions between Quinolones and <i>Escherichia coli</i> Topoisomerase IV

Katie J. Aldred, Erin J. Breland, Vladislava Vlčková et al. · Biochemistry · 2014 · 54 citations · Full text

1–5 of 8