Cellular Uptake of Platinum Nanoparticles in Human Colon Carcinoma Cells and Their Impact on Cellular Redox Systems and DNA Integrity

Joanna Pelka, Helge Gehrke, Melanie Esselen, +11

Chemical Research in Toxicology

Platinum nanoparticles and their cellular uptake and DNA platination at non-cytotoxic concentrations

Helge Gehrke, Joanna Pelka, Christian G. Hartinger, +8

Archives of Toxicology

EngineeringPlatinum NanoparticlesMetal NanoparticlesNanomaterialsNanotechnology +7

<i>In vitro</i> toxicity of amorphous silica nanoparticles in human colon carcinoma cells

Helge Gehrke, Anne Frühmesser, Joanna Pelka, +8

Nanotoxicology

NanoparticlesEngineeringNanotoxicologyBiomedical EngineeringToxicological Mechanism +16

Round robin study to evaluate the reconstructed human epidermis (RhE) model as an in vitro skin irritation test for detection of irritant activity in medical device extracts

Wim H. de Jong, Sebastian Hoffmann, Michelle Lee, +30

Toxicology in Vitro

EngineeringBiomedical EngineeringDermatologyMedical Device ExtractsSesame Oil +15

Validation of the GARD™skin Assay for Assessment of Chemical Skin Sensitizers: Ring Trial Results of Predictive Performance and Reproducibility

Henrik Johansson, Robin Gradin, Angelica Johansson, +7

Toxicological Sciences

EngineeringDendritic CellImmunologySkin Sensitizing ChemicalsSkin Allergy +26

Impact of phase I metabolism on uptake, oxidative stress and genotoxicity of the emerging mycotoxin alternariol and its monomethyl ether in esophageal cells

Christine Tiessen, Doris Ellmer, Hannes Mikula, +6

Archives of Toxicology

Reductive StressBiochemistryMycotoxin FormationLipid PeroxidationMycotoxin Alternariol +11

Role of topoisomerase inhibition and DNA repair mechanisms in the genotoxicity of alternariol and altertoxin-II

Christine Tiessen, Helge Gehrke, Christopher Kropat, +5

World Mycotoxin Journal

Dna DamageImmunotoxicologyMolecular BiologyCell DeathRedox Biology +19

DNA damaging properties of single walled carbon nanotubes in human colon carcinoma cells

Joanna Pelka, Helge Gehrke, Anja Rechel, +4

Nanotoxicology

EngineeringChemoprevention StrategyMitochondrial ActivityMolecular BiologyNanotoxicology +19

In chemico, in vitro and in vivo comparison of the skin sensitizing potential of eight unsaturated and one saturated lipid compounds

Reinhard Kreiling, Helge Gehrke, Thomas H. Broschard, +9

Regulatory Toxicology and Pharmacology

Lipid AnalysisLipid PreparationMedicineLipid CompoundsToxicology +5

Amorphous Silica Particles Relevant in Food Industry Influence Cellular Growth and Associated Signaling Pathways in Human Gastric Carcinoma Cells

A. Wittig, Helge Gehrke, Giorgia Del Favero, +6

Nanomaterials

Tumor BiologySilica ParticlesEngineeringAssociated Signaling PathwaysMedicine +13