Kirsti Hornigold

Truncating PREX2 mutations activate its GEF activity and alter gene expression regulation in NRAS-mutant melanoma

Yonathan Lissanu Deribe, Yanxia Shi, Kunal Rai et al. · Proceedings of the National Academy of Sciences · 2016 · 56 citations · Full text

Norbin Stimulates the Catalytic Activity and Plasma Membrane Localization of the Guanine-Nucleotide Exchange Factor P-Rex1

Dingxin Pan, Mark A. Barber, Kirsti Hornigold et al. · Journal of Biological Chemistry · 2016 · 30 citations · Full text

Signal Transduction, Biochemistry, Reactive Nitrogen Specie +7

Age-related decline in the resistance of mice to bacterial infection and in LPS/TLR4 pathway-dependent neutrophil responses

Kirsti Hornigold, Julia Y. Chu, Stephen A. Chetwynd et al. · Frontiers in Immunology · 2022 · 26 citations · Full text

The GPCR adaptor protein norbin suppresses the neutrophil-mediated immunity of mice to pneumococcal infection

Chiara Pantarelli, Dingxin Pan, Stephen A. Chetwynd et al. · Blood Advances · 2021 · 18 citations · Full text

Inflammatory Lung Disease, Microbial Pathogens, Lung Inflammation +23

Small-molecule inhibitors of P-Rex guanine-nucleotide exchange factors

Kirsti Hornigold, Dingxin Pan, Izabella Niewczas et al. · Small GTPases · 2022 · 17 citations · Full text