HapX-Mediated Adaption to Iron Starvation Is Crucial for Virulence of Aspergillus fumigatus

Markus Schrettl, Nicola Beckmann, John Varga, +11

PLoS Pathogens

Aspergillus FumigatusFungal Cell BiologyIron MetabolismMolecular BiologyVirulence Determinants +15

The negative cofactor 2 complex is a key regulator of drug resistance in Aspergillus fumigatus

Takanori Furukawa, Norman van Rhijn, Marcin G. Fraczek, +20

Nature Communications

Sterol Biosynthesis and Azole Tolerance Is Governed by the Opposing Actions of SrbA and the CCAAT Binding Complex

Fabio Gsaller, Peter Hortschansky, Takanori Furukawa, +9

PLoS Pathogens

EngineeringFungal Cell BiologyChemical BiologyErgosterol BiosynthesisDrug Resistance +20

The <scp>J</scp> anus transcription factor <scp>H</scp> ap <scp>X</scp> controls fungal adaptation to both iron starvation and iron excess

Fabio Gsaller, Peter Hortschansky, Sarah R. Beattie, +12

The EMBO Journal

The interplay between vacuolar and siderophore-mediated iron storage in Aspergillus fumigatus

Fabio Gsaller, Martin Eisendle, Beatrix E. Lechner, +5

Metallomics

Aspergillus FumigatusFungal Cell BiologyIron MetabolismMolecular BiologySiderophore-mediated Iron Storage +15

Triacetylfusarinine C: A urine biomarker for diagnosis of invasive aspergillosis

Martin Hoenigl, Thomas Orasch, Klaus Faserl, +9

Journal of Infection

Mechanistic Basis of pH-Dependent 5-Flucytosine Resistance in Aspergillus fumigatus

Fabio Gsaller, Takanori Furukawa, Paul D. Carr, +5

Antimicrobial Agents and Chemotherapy

The Zn2Cys6-type transcription factor LeuB cross-links regulation of leucine biosynthesis and iron acquisition in Aspergillus fumigatus

Nanbiao Long, Thomas Orasch, Shizhu Zhang, +13

PLoS Genetics

Aspergillus FumigatusFungal Cell BiologyIron MetabolismGeneticsTranscriptional Regulation +14

The Siderophore Transporters Sit1 and Sit2 Are Essential for Utilization of Ferrichrome-, Ferrioxamine- and Coprogen-Type Siderophores in Aspergillus fumigatus

Mario Aguiar, Thomas Orasch, Matthias Misslinger, +3

Journal of Fungi

The fungal CCAAT-binding complex and HapX display highly variable but evolutionary conserved synergetic promoter-specific DNA recognition

Takanori Furukawa, Mareike Thea Scheven, Matthias Misslinger, +11

Nucleic Acids Research

Ccaat MotifFungal Cell BiologyIron MetabolismGeneticsMolecular Biology +18