PNPLA1 mutations cause autosomal recessive congenital ichthyosis in golden retriever dogs and humans

Anaïs Grall, Éric Guaguère, Sandrine Planchais, +20

Nature Genetics

Genetic DisorderGeneticsPathogenesisPathologyGolden Retriever Dogs +2

G0/G1 switch gene-2 regulates human adipocyte lipolysis by affecting activity and localization of adipose triglyceride lipase

Martina Schweiger, Margret Paar, Christina Eder, +12

Journal of Lipid Research

PNPLA1 Deficiency in Mice and Humans Leads to a Defect in the Synthesis of Omega-O-Acylceramides

Susanne Grond, Thomas O. Eichmann, Sandrine Dubrac, +9

Journal of Investigative Dermatology

BiochemistryBiochemical GeneticsHumans LeadsPnpla1 DeficiencyPharmacology

ABHD5 stimulates PNPLA1-mediated ω-O-acylceramide biosynthesis essential for a functional skin permeability barrier

Benedikt Kien, Susanne Grond, Guenter Haemmerle, +3

Journal of Lipid Research

Safety of baricitinib for the treatment of atopic dermatitis over a median of 1.6 years and up to 3.9 years of treatment: an updated integrated analysis of eight clinical trials

Thomas Bieber, Norito Katoh, Eric L. Simpson, +10

Journal of Dermatological Treatment

Burden of Moderate to Severe Atopic Dermatitis in Adults from France, Italy, and the UK: Patient-Reported Outcomes and Treatment Patterns

C. Elise Kleyn, S. Barbarot, Catherine Reed, +6

Dermatology and Therapy

Baricitinib Safety for Events of Special Interest in Populations at Risk: Analysis from Randomised Trial Data Across Rheumatologic and Dermatologic Indications

Peter C. Taylor, Thomas Bieber, Rieke Alten, +8

Advances in Therapy

G0/G1 Switch Gene 2 Regulates Cardiac Lipolysis

Christoph Heier, Franz P.W. Radner, Tarek Moustafa, +12

Journal of Biological Chemistry

Metabolic SyndromeCardiomyopathyHeart FailureMolecular PhysiologySignal Transduction +13

Skin Barrier Development Depends on CGI-58 Protein Expression during Late-Stage Keratinocyte Differentiation

Susanne Grond, Franz P.W. Radner, Thomas O. Eichmann, +14

Journal of Investigative Dermatology

Different expression of cytokines in survivors and non-survivors from MODS following cardiovascular surgery.

Armin Sablotzki, Dehne Mg, Ivar Friedrich, +5

PubMed