Hsi-Hsien Hsieh

Macrophage-to-endothelial cell crosstalk by the cholesterol metabolite 27HC promotes atherosclerosis in male mice

Liming Yu, Lin Xu, Haiyan Chu et al. · Nature Communications · 2023 · 41 citations · Full text

Structure-based design, synthesis and evaluation of novel anthra[1,2-d]imidazole-6,11-dione derivatives as telomerase inhibitors and potential for cancer polypharmacology

Chun‐Liang Chen, Deh‐Ming Chang, Tsung‐Chih Chen et al. · European Journal of Medicinal Chemistry · 2012 · 38 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Polymer-drug Conjugate +11

The serine protease inhibitor serpinB2 binds and stabilizes p21 in senescent cells

Hsi-Hsien Hsieh, Ying‐Chieh Chen, Jing-Ru Jhan et al. · Journal of Cell Science · 2017 · 38 citations · Full text

Affect Senescence, Signal Transduction, Signaling Pathway +15

Structure-based design, synthesis and biological evaluation of novel anthra[1,2-d]imidazole-6,11-dione homologues as potential antitumor agents

Tsung‐Chih Chen, Dah‐Shyong Yü, Kuo-Feng Huang et al. · European Journal of Medicinal Chemistry · 2013 · 24 citations

Medicinal Chemistry, Biochemistry, Medicine +8

CDC25B induces cellular senescence and correlates with tumor suppression in a p53-dependent manner

Ying‐Chieh Chen, Hsi-Hsien Hsieh, Hsi-Chi Chang et al. · Journal of Biological Chemistry · 2021 · 22 citations · Full text