α9‐ and α7‐containing receptors mediate the pro‐proliferative effects of nicotine in the A549 adenocarcinoma cell line

Vanessa Mucchietto, Francesca Fasoli, Susanna Pucci, +10

British Journal of Pharmacology

Choline and nicotine increase glioblastoma cell proliferation by binding and activating α7- and α9- containing nicotinic receptors

Susanna Pucci, Francesca Fasoli, Milena Moretti, +9

Pharmacological Research

GliomaMedicineNicotineReceptor (Biochemistry)Pharmacology +1

<scp>CC</scp>4, a dimer of cytisine, is a selective partial agonist at α4β2/α6β2<scp>nAChR</scp>with improved selectivity for tobacco smoking cessation

Mariaelvina Sala, Daniela Braida, Luca Pucci, +12

British Journal of Pharmacology

Chronic nicotine and withdrawal affect glutamatergic but not nicotinic receptor expression in the mesocorticolimbic pathway in a region-specific manner

Francesco Pistillo, Francesca Fasoli, Milena Moretti, +4

Pharmacological Research

Tobacco ControlNeurophysiologyAddictionMedicinePhysiology +11

In vivo chronic nicotine exposure differentially and reversibly affects upregulation and stoichiometry of α4β2 nicotinic receptors in cortex and thalamus

Francesca Fasoli, Milena Moretti, Michèle Zoli, +6

Neuropharmacology

Molecular NeuroscienceSynaptic SignalingNeurophysiologyMedicineSynaptic Transmission +12

Chemistry and Pharmacology of a Series of Unichiral Analogues of 2-(2-Pyrrolidinyl)-1,4-benzodioxane, Prolinol Phenyl Ether, and Prolinol 3-Pyridyl Ether Designed as α4β2-Nicotinic Acetylcholine Receptor Agonists

Cristiano Bolchi, Ermanno Valoti, Cecilia Gotti, +9

Journal of Medicinal Chemistry

Organic ChemistryExperimental PharmacologyPharmaceutical ChemistryChemical DerivativeMolecular Pharmacology +15

The cytisine derivatives, CC4 and CC26, reduce nicotine-induced conditioned place preference in zebrafish by acting on heteromeric neuronal nicotinic acetylcholine receptors

Luisa Ponzoni, Daniela Braida, Luca Pucci, +9

Psychopharmacology

Behavioral NeuroscienceMedicineNicotinePhysiologyNeurotransmitter +7

Potent Antiglioblastoma Agents by Hybridizing the Onium-Alkyloxy-Stilbene Based Structures of an α7-nAChR, α9-nAChR Antagonist and of a Pro-Oxidant Mitocan

Francesco Bavo, Susanna Pucci, Francesca Fasoli, +14

Journal of Medicinal Chemistry

Chemoprevention StrategyMitochondrial Atp ProductionPharmacotherapyChemical Biologyα9-Nachr Antagonist +20

A Promising PET Tracer for Imaging of α7 Nicotinic Acetylcholine Receptors in the Brain: Design, Synthesis, and in Vivo Evaluation of a Dibenzothiophene-Based Radioligand

Rodrigo Teodoro, Matthias Scheunemann, Winnie Deuther‐Conrad, +13

Molecules

Modification of the anabaseine pyridine nucleus allows achieving binding and functional selectivity for the α3β4 nicotinic acetylcholine receptor subtype

Carlo Matera, Marta Quadri, Miriam Sciaccaluga, +7

European Journal of Medicinal Chemistry

Signal TransductionBiochemistryFunctional SelectivityMedicineSynaptic Transmission +6