Emily G. Knox

A divalent siRNA chemical scaffold for potent and sustained modulation of gene expression throughout the central nervous system

Julia F. Alterman, Bruno M.D.C. Godinho, Matthew Hassler et al. · Nature Biotechnology · 2019 · 220 citations

Molecular Neuroscience, Signal Transduction, Medicine +10

Microbial-derived metabolites induce actin cytoskeletal rearrangement and protect blood-brain barrier function

Emily G. Knox, María R. Aburto, Carmen Tessier et al. · iScience · 2022 · 80 citations · Full text

Chemical engineering of therapeutic siRNAs for allele-specific gene silencing in Huntington’s disease models

Faith Conroy, Rachael Miller, Julia F. Alterman et al. · Nature Communications · 2022 · 46 citations · Full text

The gut microbiota is important for the maintenance of blood–cerebrospinal fluid barrier integrity

Emily G. Knox, C. M. Lynch, Ye‐Seul Lee et al. · European Journal of Neuroscience · 2022 · 31 citations · Full text

Dysbiosis, Host-microbe Interactions, Immunology +20

Comparative route of administration studies using therapeutic siRNAs show widespread gene modulation in Dorset sheep

Chantal Ferguson, Bruno M.D.C. Godinho, Julia F. Alterman et al. · JCI Insight · 2021 · 28 citations · Full text