Nikolas H. Chmiel

Inherited variants of MYH associated with somatic G:C→T:A mutations in colorectal tumors

Nada Al Tassan, Nikolas H. Chmiel, Julie Maynard et al. · Nature Genetics · 2002 · 1.4K citations

Tumor Biology, Somatic Variant, Inherited Variants +10

DNA-mediated charge transport for DNA repair

Elizabeth M. Boon, Alison L. Livingston, Nikolas H. Chmiel et al. · Proceedings of the National Academy of Sciences · 2003 · 223 citations · Full text

Genome Instability, Dna Damage, Redox Process +12

Insight into the Functional Consequences of Inherited Variants of the hMYH Adenine Glycosylase Associated with Colorectal Cancer: Complementation Assays with hMYH Variants and Pre-steady-state Kinetics of the Corresponding Mutated E.coli Enzymes

Nikolas H. Chmiel, Alison L. Livingston, Sheila S. David · Journal of Molecular Biology · 2003 · 91 citations

Complementation Assays, Biochemistry, Inherited Variants +9

Efficient recognition of substrates and substrate analogs by the adenine glycosylase MutY requires the C-terminal domain

Nikolas H. Chmiel · Nucleic Acids Research · 2001 · 84 citations · Full text

Insight into the functional consequences of hMYH variants associated with colorectal cancer: distinct differences in the adenine glycosylase activity and the response to AP endonucleases of Y150C and G365D murine MYH

Mary Ann Pope, Nikolas H. Chmiel, Sheila S. David · DNA repair · 2004 · 55 citations

Hmyh Variants, Oncology, Medicine +7