scGPT: toward building a foundation model for single-cell multi-omics using generative AI

Haotian Cui, Hassaan Maan, Kuan Pang, +3

Nature Methods

Artificial IntelligenceEngineeringMachine LearningSingle-cell Multi-omicsMedicine +12

scGPT: Towards Building a Foundation Model for Single-Cell Multi-omics Using Generative AI

Haotian Cui, Hassaan Maan, Kuan Pang, +2

Artificial IntelligenceLlm Fine-tuningEngineeringMachine LearningGenetics +26

AGILE platform: a deep learning powered approach to accelerate LNP development for mRNA delivery

Yue Xu, Shihao Ma, Haotian Cui, +9

Nature Communications

Stretchable ultrasonic arrays for the three-dimensional mapping of the modulus of deep tissue

Hongjie Hu, Yuxiang Ma, Xiaoxiang Gao, +32

Nature Biomedical Engineering

Medical UltrasoundEngineeringMechanical EngineeringBiomedical EngineeringSerial Assessment +20

Towards multimodal foundation models in molecular cell biology

Haotian Cui, Alejandro Tejada-Lapuerta, Maria Brbić, +6

Nature

EngineeringComputational BiologyBiological ModelMulticellular SystemCell Biology +1

DeepVelo: deep learning extends RNA velocity to multi-lineage systems with cell-specific kinetics

Haotian Cui, Hassaan Maan, Maria Vladoiu, +3

Genome biology

AGILE Platform: A Deep Learning-Powered Approach to Accelerate LNP Development for mRNA Delivery

Yue Xu, Shihao Ma, Haotian Cui, +7

NanotherapeuticsEngineeringMolecular BiologyGene DeliveryBiomedical Engineering +28

scGPT-spatial: Continual Pretraining of Single-Cell Foundation Model for Spatial Transcriptomics

Chloe Xueqi Wang, Haotian Cui, A. Zhang, +3

DeepVelo: Deep Learning extends RNA velocity to multi-lineage systems with cell-specific kinetics

Haotian Cui, Hassaan Maan, Michael D. Taylor, +1

EngineeringTranscriptomics TechnologyGene Regulatory NetworkCell DifferentiationTrajectory Analysis +22

Multiscale interactome analysis coupled with off-target drug predictions reveals drug repurposing candidates for human coronavirus disease

Michael G. Sugiyama, Haotian Cui, Dar’ya S. Redka, +20

Scientific Reports

Drug TargetEngineeringImmunologyMolecular BiologyHost Cell Proteins +22