Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation

Thomas T. Sato, Yuzuru Tozawa, Urban Deutsch, +7

Nature

Receptor TyrosineAngiogenesisSignal TransductionSignaling PathwayReceptor Tyrosine Kinase +8

EZH1 Mediates Methylation on Histone H3 Lysine 27 and Complements EZH2 in Maintaining Stem Cell Identity and Executing Pluripotency

Xiaohua Shen, Yingchun Liu, Yu-Jung Hsu, +5

Molecular Cell

Histone ModificationsChromatinInduced Pluripotent Stem CellDevelopmental BiologyExecuting Pluripotency +11

BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis

Matthew C. Canver, Elenoe C. Smith, Falak Sher, +16

Nature

Natural SciencesBcl11a Enhancer DissectionMolecular BiologyGenome EngineeringGene Editing +4

Essential role for the peroxiredoxin Prdx1 in erythrocyte antioxidant defence and tumour suppression

Carola A. Neumann, Daniela S. Krause, Christopher V. Carman, +7

Nature

InflammationReductive StressEssential RoleRedox RegulatorMedicine +10

Arrested development of embryonic red cell precursors in mouse embryos lacking transcription factor GATA-1.

Yuko Fujiwara, Carol Browne, K. C. Cunniff, +2

Proceedings of the National Academy of Sciences

GeneticsArrested DevelopmentMouse EmbryosEpigeneticsEmbryology +16

Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells

Robert S. Ohgami, Dean R. Campagna, Eric Lieberman Greer, +7

Nature Genetics

Iron DeficiencyErythroid CellsBiochemistryHeme HomeostasisIron Metabolism +11

The T Cell Leukemia Oncoprotein SCL/tal-1 Is Essential for Development of All Hematopoietic Lineages

Catherine Porcher, Wojciech Swat, Karen Rockwell, +3

Cell

Hematological MalignancyChromatinDevelopmental BiologyLymphocyte DevelopmentMixed-phenotype Acute Leukemia +7

FOG, a Multitype Zinc Finger Protein, Acts as a Cofactor for Transcription Factor GATA-1 in Erythroid and Megakaryocytic Differentiation

Alice P. Tsang, Jane E. Visvader, C.Alexander Turner, +5

Cell

Cell LineageDevelopmental BiologyDevelopmental GeneticsGeneticsMegakaryocytic Differentiation +5

A Critical Role for DNA End-Joining Proteins in Both Lymphogenesis and Neurogenesis

Yijie Gao, Sun Yi, Karen M. Frank, +18

Cell

ChromatinGenome InstabilityDna End-joining ProteinsDevelopmental BiologyCritical Role +5

A lineage-selective knockout establishes the critical role of transcription factor GATA-1 in megakaryocyte growth and platelet development

Ramesh A. Shivdasani, Yuko Fujiwara, Michael A. McDevitt, +1

The EMBO Journal

Transcriptional RegulationCell LineageDevelopmental BiologyGeneticsLineage-selective Knockout +8