Gulinuer Wumaier

PTPL1 suppresses lung cancer cell migration via inhibiting TGF-β1-induced activation of p38 MAPK and Smad 2/3 pathways and EMT

Ning Zhu, Xiujuan Zhang, Hai Zou et al. · Acta Pharmacologica Sinica · 2021 · 26 citations · Full text

Life Sciences, Cell Biology, Oncology +12

Discovery and optimization of 4-anilinoquinazoline derivatives spanning ATP binding site and allosteric site as effective EGFR-C797S inhibitors

Dou Dou, Jie Wang, Yunjin Qiao et al. · European Journal of Medicinal Chemistry · 2022 · 26 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Design, synthesis and biological evaluation of potent EGFR kinase inhibitors against 19D/T790M/C797S mutation

Zhicheng Su, Tingyuan Yang, Jie Wang et al. · Bioorganic & Medicinal Chemistry Letters · 2020 · 24 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +14

Cefminox, a Dual Agonist of Prostacyclin Receptor and Peroxisome Proliferator-Activated Receptor-Gamma Identified by Virtual Screening, Has Therapeutic Efficacy against Hypoxia-Induced Pulmonary Hypertension in Rats

Jingwen Xia, Yang Li, Liang Dong et al. · Frontiers in Pharmacology · 2018 · 21 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Protein tyrosine phosphatase L1 represses endothelial-mesenchymal transition by inhibiting IL-1β/NF-κB/Snail signaling

Xiaomin Wei, Gulinuer Wumaier, Ning Zhu et al. · Acta Pharmacologica Sinica · 2020 · 20 citations · Full text

Life Sciences, Biochemistry, Cell Biology +13