Kazuhisa Takahashi

Pembrolizumab versus chemotherapy for previously untreated, PD-L1-expressing, locally advanced or metastatic non-small-cell lung cancer (KEYNOTE-042): a randomised, open-label, controlled, phase 3 trial

Tony Mok, Yi‐Long Wu, Iveta Kudaba et al. · The Lancet · 2019 · 3.2K citations · Full text

A cross-population atlas of genetic associations for 220 human phenotypes

Saori Sakaue, Masahiro Kanai, Yosuke Tanigawa et al. · Nature Genetics · 2021 · 2.2K citations · Full text

Genome-wide Association Study, Haplotype Determination, Human Phenotypes +8

Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases

Kazuyoshi Ishigaki, Masato Akiyama, Masahiro Kanai et al. · Nature Genetics · 2020 · 566 citations · Full text

Genome-wide Association Study, Disease Susceptibility, Genotype-phenotype Association +12

Gefitinib Alone Versus Gefitinib Plus Chemotherapy for Non–Small-Cell Lung Cancer With Mutated Epidermal Growth Factor Receptor: NEJ009 Study

Yukio Hosomi, Satoshi Morita, Shunichi Sugawara et al. · Journal of Clinical Oncology · 2019 · 473 citations

Alternative splicing of CD44 mRNA by ESRP1 enhances lung colonization of metastatic cancer cell

Toshifumi Yae, Kenji Tsuchihashi, Takatsugu Ishimoto et al. · Nature Communications · 2012 · 378 citations · Full text

Medicine, Cd44 Mrna, Cancer Cell Biology +9