BRCAness, SLFN11, and RB1 loss predict response to topoisomerase I inhibitors in triple-negative breast cancers

Florence Coussy, Rania El Botty, Sophie Château‐Joubert, +31

Science Translational Medicine

PLK1 inhibition exhibits strong anti-tumoral activity in CCND1-driven breast cancer metastases with acquired palbociclib resistance

Élodie Montaudon, Joanna Nikitorowicz-Buniak, Laura Sourd, +35

Nature Communications

Oxidative phosphorylation is a metabolic vulnerability of endocrine therapy and palbociclib resistant metastatic breast cancers

Rania El Botty, Ludivine Morriset, Élodie Montaudon, +24

Nature Communications

Topography, Composition and Structure of Incipient Randall Plaque at the Nanoscale Level

Cécile Verrier, Dominique Bazin, Léa Huguet, +9

The Journal of Urology

Stiripentol protects against calcium oxalate nephrolithiasis and ethylene glycol poisoning

Marine Le Dudal, Léa Huguet, Joëlle Perez, +12

Journal of Clinical Investigation

ABCC6 Deficiency Promotes Development of Randall Plaque

Emmanuel Letavernier, Gilles Kauffenstein, Léa Huguet, +16

Journal of the American Society of Nephrology

A large collection of integrated genomically characterized patient‐derived xenografts highlighting the heterogeneity of triple‐negative breast cancer

Florence Coussy, Leanne de Koning, Marion Lavigne, +27

International Journal of Cancer

Combination of PI3K and MEK inhibitors yields durable remission in PDX models of PIK3CA-mutated metaplastic breast cancers

Florence Coussy, Rania El Botty, Marion Lavigne, +17

Journal of Hematology & Oncology

Calcium and vitamin D have a synergistic role in a rat model of kidney stone disease

Emmanuel Letavernier, Cécile Verrier, Florent Goussard, +6

Kidney International

UrologyRenal FunctionKidney Stone DiseaseMedicinePhysiology +8

Homologous recombination deficiency derived from whole-genome sequencing predicts platinum response in triple-negative breast cancers

Petra ter Brugge, Sarah C. Moser, Ivan Bièche, +30

Nature Communications