Reprogramming to recover youthful epigenetic information and restore vision

Yuancheng Ryan Lu, Benedikt Brommer, Xiao Tian, +26

Nature

ChromatinMedicineGeneticsYouthful Epigenetic InformationEpigenetic Change +4

Soluble CD163 Made by Monocyte/Macrophages Is a Novel Marker of HIV Activity in Early and Chronic Infection Prior to and After Anti-retroviral Therapy

Tricia H. Burdo, Margaret R. Lentz, Patrick Autissier, +6

The Journal of Infectious Diseases

InflammationPrimary ImmunodeficiencyChronic Hiv InfectionHuman RetrovirusImmunology +13

Increased Monocyte Turnover from Bone Marrow Correlates with Severity of SIV Encephalitis and CD163 Levels in Plasma

Tricia H. Burdo, Caroline Soulas, Krystyna Orzechowski, +6

PLoS Pathogens

A small peptide antagonist of the Fas receptor inhibits neuroinflammation and prevents axon degeneration and retinal ganglion cell death in an inducible mouse model of glaucoma

Anitha Krishnan, Andrew J. Kocab, David N. Zacks, +2

Journal of Neuroinflammation

Chronic Morphine Administration Delays Wound Healing by Inhibiting Immune Cell Recruitment to the Wound Site

Josephine L. Martin, Lisa Koodie, Anitha Krishnan, +3

American Journal Of Pathology

Morphine induced exacerbation of sepsis is mediated by tempering endotoxin tolerance through modulation of miR-146a

Santanu Banerjee, Jingjing Meng, Subhas Das, +6

Scientific Reports

Lung InflammationPain MedicineImmunologyMolecular PainOxidative Stress +14

Overexpression of Soluble Fas Ligand following Adeno-Associated Virus Gene Therapy Prevents Retinal Ganglion Cell Death in Chronic and Acute Murine Models of Glaucoma

Anitha Krishnan, Fei Fei, Alexander Jones, +4

The Journal of Immunology

Morphine Modulation of Toll-Like Receptors in Microglial Cells Potentiates Neuropathogenesis in a HIV-1 Model of Coinfection with Pneumococcal Pneumoniae

Rajib Dutta, Anitha Krishnan, Siba R. Das, +7

Journal of Neuroscience

Mouse model of ocular hypertension with retinal ganglion cell degeneration

Ryo Mukai, Dong Ho Park, Yoko Okunuki, +8

PLoS ONE

Reversal of ageing- and injury-induced vision loss by Tet-dependent epigenetic reprogramming

Yuancheng Ryan Lu, Anitha Krishnan, Benedikt Brommer, +23

Epigenetic ChangeBiogerontologyDna Methylation AgeOptogeneticsEpigenetics +17