Globular adiponectin increases GLUT4 translocation and glucose uptake but reduces glycogen synthesis in rat skeletal muscle cells

Rolando B. Ceddia, Romel Somwar, Adriano Maida, +3

Diabetologia

Insulin SignalingEnergy MetabolismGlycosylationBiochemistryPhysiology +9

The Adult Mouse and Human Pancreas Contain Rare Multipotent Stem Cells that Express Insulin

Simon R. Smukler, Margot E. Arntfield, Rozita Razavi, +9

Cell stem cell

Regenerative MedicineInsulin SignalingDevelopmental BiologyMedicineDiabetes +11

Free Fatty Acid–Induced Reduction in Glucose-Stimulated Insulin Secretion

Andrei I. Oprescu, George Bikopoulos, Anthony E. Naassan, +9

Diabetes

Thermogenic Capacity Is Antagonistically Regulated in Classical Brown and White Subcutaneous Fat Depots by High Fat Diet and Endurance Training in Rats

Michelle V. Wu, George Bikopoulos, Steven Hung, +1

Journal of Biological Chemistry

Metabolic RateHigh Fat DietEndurance TrainingCaloric RestrictionBody Composition +21

Differential activation of ER stress and apoptosis in response to chronically elevated free fatty acids in pancreatic β-cells

Elida Lai, George Bikopoulos, Michael B. Wheeler, +2

American Journal of Physiology-Endocrinology and Metabolism

ApoptosisCell DeathEr StressInsulin SignalingDifferential Activation +18

The Zn2+-transporting Pathways in Pancreatic β-Cells

Armen V. Gyulkhandanyan, Simon J. Craddock Lee, George Bikopoulos, +2

Journal of Biological Chemistry

Insulin BiosynthesisCytoskeletonOptogeneticsCellular PhysiologyInsulin Signaling +16

High-fat diet induces skeletal muscle oxidative stress in a fiber type-dependent manner in rats

Ricardo A. Pinho, Diane M. Sepa-Kishi, George Bikopoulos, +6

Free Radical Biology and Medicine

ObesityMetabolic SyndromeNutritionBody CompositionBiochemistry +9

Identification of a WD40 Repeat-Containing Isoform of PHIP as a Novel Regulator of β-Cell Growth and Survival

Alexey Podcheko, Paul A. Northcott, George Bikopoulos, +5

Molecular and Cellular Biology

Distinct mechanisms involving diacylglycerol, ceramides, and inflammation underlie insulin resistance in oxidative and glycolytic muscles from high fat-fed rats

Shailee Jani, Daniel Da Eira, Ishvinder Hadday, +4

Scientific Reports

Ex vivo transcriptional profiling of human pancreatic islets following chronic exposure to monounsaturated fatty acids

George Bikopoulos, Aurélio da Silva Pimenta, Simon J. Craddock Lee, +6

Journal of Endocrinology

Metabolic SyndromeInsulin SignalingTranscriptional ProfilingBiochemistryFatty Acids +12