Tomoko Ashizawa

Enantioselective Henry Reaction Catalyzed by Optically Active Ketoiminatocobalt Complexes

Youichi Kogami, Takahiro Nakajima, Tomoko Ashizawa et al. · Chemistry Letters · 2004 · 97 citations

Engineering, β-Nitro Alcohols, Active Ketoiminatocobalt Complexes +7

Catalytic <i>atropo</i>-Enantioselective Reduction of Biaryl Lactones to Axially Chiral Biaryl Compounds

Tomoko Ashizawa, Saiko Tanaka, Tohru Yamada · Organic Letters · 2008 · 87 citations

Biaryl Lactones, Engineering, Chiral Biaryl Compounds +10

Enantioselective 1,3-Dipolar Cycloaddition Reaction of Nitrones with α,β-Unsaturated Aldehydes Catalyzed by Cationic 3-Oxobutylideneaminatocobalt(III) Complexes

Satoko Kezuka, Natsuki Ohtsuki, Tsuyoshi Mita et al. · Bulletin of the Chemical Society of Japan · 2003 · 51 citations

Chemical Engineering, Absolute Configuration, Engineering +12

Catalytic <i>atropo</i>-Enantioselective Preparation of Axially Chiral Biaryl Compounds

Tomoko Ashizawa, Tohru Yamada · Chemistry Letters · 2009 · 45 citations

Dramatic Rate Acceleration, Biaryl Lactones, Engineering +11

Discovery of Clinical Candidate <i>N</i>-((1<i>S</i>)-1-(3-Fluoro-4-(trifluoromethoxy)phenyl)-2-methoxyethyl)-7-methoxy-2-oxo-2,3-dihydropyrido[2,3-<i>b</i>]pyrazine-4(1<i>H</i>)-carboxamide (TAK-915): A Highly Potent, Selective, and Brain-Penetrating Phosphodiesterase 2A Inhibitor for the Treatment of Cognitive Disorders

Satoshi Mikami, Shinji Nakamura, Tomoko Ashizawa et al. · Journal of Medicinal Chemistry · 2017 · 37 citations · Full text

Brain-penetrating Phosphodiesterase 2A, Brain Penetration, Pharmacotherapy +17