Treatment of Cancer Patients With a Serotype 5/3 Chimeric Oncolytic Adenovirus Expressing GMCSF

Anniina Koski, Lotta Kangasniemi, Sophie Escutenaire, +22

Molecular Therapy

Oncolytic Adenovirus Coding for Granulocyte Macrophage Colony-Stimulating Factor Induces Antitumoral Immunity in Cancer Patients

Vincenzo Cerullo, Sari Pesonen, Iulia Diaconu, +23

Cancer Research

ImmunologyImmunologic MechanismCancer PatientsImmunotherapyNatural Killer Cells +14

Oncolytic Adenovirus ICOVIR-7 in Patients with Advanced and Refractory Solid Tumors

Petri Nokisalmi, Sari Pesonen, Sophie Escutenaire, +18

Clinical Cancer Research

Integrin targeted oncolytic adenoviruses Ad5‐D24‐RGD and Ad5‐RGD‐D24‐GMCSF for treatment of patients with advanced chemotherapy refractory solid tumors

Sari Pesonen, Iulia Diaconu, Vincenzo Cerullo, +18

International Journal of Cancer

Combination of gemcitabine and Ad5/3-Δ24, a tropism modified conditionally replicating adenovirus, for the treatment of ovarian cancer

Mari Raki, Anna Kanerva, Ari Ristimäki, +6

Gene Therapy

Molecular BiologyCancer Cell BiologyCancer TreatmentMedicineCell Biology +3

SPECT/CT imaging of radiolabeled cubosomes and hexosomes for potential theranostic applications

Christa Nilsson, Brianda Barrios‐Lopez, Annukka Kallinen, +11

Biomaterials

EngineeringMedical ImagingMicroscopyPotential Theranostic ApplicationsBiomedical Imaging +7

Prolonged systemic circulation of chimeric oncolytic adenovirus Ad5/3-Cox2L-D24 in patients with metastatic and refractory solid tumors

Sari Pesonen, Petri Nokisalmi, Sophie Escutenaire, +19

Gene Therapy

MedicinePathologyRefractory Solid TumorsOncologyRadiation Oncology +4

Pre-Targeting and Direct Immunotargeting of Liposomal Drug Carriers to Ovarian Carcinoma

Julia Lehtinen, Mari Raki, Kim Bergström, +11

PLoS ONE

A heparan sulfate-targeted conditionally replicative adenovirus, Ad5.pk7-Δ24, for the treatment of advanced breast cancer

Tuuli Ranki, Anna Kanerva, Ari Ristimäki, +7

Gene Therapy

Advanced Breast CancerImmunologyReplicative AdenovirusMedicineRadiation Oncology +4

Induction of Interferon Pathways Mediates In Vivo Resistance to Oncolytic Adenovirus

Ilkka Liikanen, Vladia Monsurrò, Laura Ahtiainen, +12

Molecular Therapy

Oncolytic AdenovirusesInterferon Pathways MediatesTumor RecurrenceViral PathogenesisImmunology +12