Miranda L. Tradewell

Gain and loss of function of ALS-related mutations of TARDBP (TDP-43) cause motor deficits in vivo

Edor Kabashi, Miranda L. Tradewell, Patrick A. Dion et al. · Human Molecular Genetics · 2009 · 412 citations

Als-related Mutations, Motor Dysfunction, Genetics +16

Arginine methylation by PRMT1 regulates nuclear-cytoplasmic localization and toxicity of FUS/TLS harbouring ALS-linked mutations

Miranda L. Tradewell, Zhenbao Yu, Michael Tibshirani et al. · Human Molecular Genetics · 2011 · 198 citations · Full text

Calcium dysregulation, mitochondrial pathology and protein aggregation in a culture model of amyotrophic lateral sclerosis: Mechanistic relationship and differential sensitivity to intervention

Miranda L. Tradewell, Laura A. Cooper, Sandra Minotti et al. · Neurobiology of Disease · 2011 · 74 citations · Full text

Amyotrophic Lateral Sclerosis, Mitochondrial Pathology, Protein Aggregation +7

Cytoplasmic sequestration of FUS/TLS associated with ALS alters histone marks through loss of nuclear protein arginine methyltransferase 1

Michael Tibshirani, Miranda L. Tradewell, Katie R. Mattina et al. · Human Molecular Genetics · 2014 · 58 citations · Full text

Mitochondrial and Axonal Abnormalities Precede Disruption of the Neurofilament Network in a Model of Charcot-Marie-Tooth Disease Type 2E and Are Prevented by Heat Shock Proteins in a Mutant-Specific Fashion

Miranda L. Tradewell, Heather D. Durham, Walter E. Mushynski et al. · Journal of Neuropathology & Experimental Neurology · 2009 · 53 citations · Full text

Molecular Biology, Cytoskeleton, Cellular Neurobiology +16