RNA interference targeting cathepsin L and Z-like cysteine proteases of Onchocerca volvulus confirmed their essential function during L3 molting

Sara Lustigman, Jun Zhang, Jing Liu, +2

Molecular and Biochemical Parasitology

Protein FunctionCathepsin LBiochemistryRna InterferenceNatural Sciences +5

Cathepsin L Is Essential for Embryogenesis and Development ofCaenorhabditis elegans

Sarwar Hashmi, Collette Britton, Jing Liu, +3

Journal of Biological Chemistry

<i>Ancylostoma caninum</i> MTP-1, an Astacin-Like Metalloprotease Secreted by Infective Hookworm Larvae, Is Involved in Tissue Migration

Angela Williamson, Sara Lustigman, Yelena Oksov, +7

Infection and Immunity

Repositioning of an existing drug for the neglected tropical disease Onchocerciasis

Christian Johannes Gloeckner, Amanda L. Garner, Fana B. Mersha, +6

Proceedings of the National Academy of Sciences

Molecular Cloning, Biochemical Characterization, and Partial Protective Immunity of the Heme-Binding Glutathione<i>S</i>-Transferases from the Human Hookworm<i>Necator americanus</i>

Bin Zhan, Samïrah Perally, Peter M. Brophy, +16

Infection and Immunity

ImmunologyRedox BiologyHookworm Glutathione S-transferasesParasite GenomicsParasite Blood Feeding +14

A gene family of cathepsin L-like proteases of filarial nematodes are associated with larval molting and cuticle and eggshell remodeling

David B. Guiliano, Xiqiang Hong, James H. McKerrow, +5

Molecular and Biochemical Parasitology

BiologyDevelopmental BiologyMedicinePathogenesisMorphogenesis +7

PfRH5: A Novel Reticulocyte-Binding Family Homolog of Plasmodium falciparum that Binds to the Erythrocyte, and an Investigation of Its Receptor

Marilis Rodriguez, Sara Lustigman, Estrella Montero, +2

PLoS ONE

Characterization of a Novel Filarial Serine Protease Inhibitor, Ov-SPI-1, from Onchocerca volvulus, with Potential Multifunctional Roles during Development of the Parasite

Louise Ford, David B. Guiliano, Yelena Oksov, +5

Journal of Biological Chemistry

Protease InhibitorsBiologyOnchocerca VolvulusSequence Tag DatasetLocalization Data +13

The Caenorhabditis elegans Cathepsin Z-like Cysteine Protease, Ce-CPZ-1, Has a Multifunctional Role during the Worms' Development

Sarwar Hashmi, Jun Zhang, Yelena Oksov, +1

Journal of Biological Chemistry

Functional Analysis of the Cathepsin-Like Cysteine Protease Genes in Adult Brugia malayi Using RNA Interference

Louise Ford, Jun Zhang, Jing Liu, +4

PLoS neglected tropical diseases