Deep imaging of bone marrow shows non-dividing stem cells are mainly perisinusoidal

Melih Acar, Kiranmai S. Kocherlakota, Malea M. Murphy, +7

Nature

Bone Marrow FailureMedical ImagingMedicineAdult Stem CellBiomedical Imaging +9

Thirty-One Flavors of Drosophila Rab Proteins

Jun Zhang, Karen L. Schulze, P. Robin Hiesinger, +7

Genetics

GeneticsMolecular BiologyMolecular GeneticsCytoskeletonProtein Genetics +16

Intracranial inhibition of platelet-derived growth factor-mediated glioblastoma cell growth by an orally active kinase inhibitor of the 2-phenylaminopyrimidine class.

John A. Alberta, P R Zdunek, Melih Acar, +5

PubMed

PharmacotherapyHigh-grade GliomasAnimal Cell LinesGliomaTumor Biology +15

Rumi Is a CAP10 Domain Glycosyltransferase that Modifies Notch and Is Required for Notch Signaling

Melih Acar, Hamed Jafar‐Nejad, Hideyuki Takeuchi, +6

Cell

MedicineGeneticsCap10 Domain GlycosyltransferaseGlycobiologyNatural Sciences +6

A perisinusoidal niche for extramedullary haematopoiesis in the spleen

Christopher N. Inra, Bo Zhou, Melih Acar, +4

Nature

HematologyHistopathologyPathologyLymphatic SystemAnatomy +2

Sec15, a Component of the Exocyst, Promotes Notch Signaling during the Asymmetric Division of Drosophila Sensory Organ Precursors

Hamed Jafar‐Nejad, Hillary K Andrews, Melih Acar, +5

Developmental Cell

BiologyAsymmetric DivisionPromotes Notch SignalingSignal TransductionDevelopmental Biology +10

Hematopoietic Stem Cells Do Not Depend on N-Cadherin to Regulate Their Maintenance

Mark J. Kiel, Melih Acar, Glenn L. Radice, +1

Cell stem cell

Developmental BiologyTheir MaintenanceMedicineAdult Stem CellHematology +5

Senseless acts as a binary switch during sensory organ precursor selection

Hamed Jafar‐Nejad, Melih Acar, Riitta Nolo, +4

Genes & Development

Sensory Organ PrecursorBrain MechanismGene Regulatory NetworkOptogeneticsSensory Systems +27

Lethal Giant Discs, a Novel C2-Domain Protein, Restricts Notch Activation during Endocytosis

Jennifer Childress, Melih Acar, Chunyao Tao, +1

Current Biology

Developmental BiologyNovel C2-domain ProteinMedicineEndocytic PathwayIntracellular Trafficking +8

Prdm16 is required for the maintenance of neural stem cells in the postnatal forebrain and their differentiation into ependymal cells

Issei S. Shimada, Melih Acar, Rebecca J. Burgess, +2

Genes & Development