R. Adam Mosey

Stereoselective syntheses of quaternary substituted α-amino acids using oxazol-5-(4H)-ones

R. Adam Mosey, Jason S. Fisk, Jetze J. Tepe · Tetrahedron Asymmetry · 2008 · 153 citations

Engineering, Stereoselective Syntheses, Organic Chemistry +3

Inhibition of the Human Proteasome by Imidazoline Scaffolds

Lauren M. Azevedo, Theresa A. Lansdell, Jacob R. Ludwig et al. · Journal of Medicinal Chemistry · 2013 · 41 citations · Full text

Cytoskeleton, Pharmacotherapy, Competitive Proteasome Inhibitors +20

Versatile approach to α-alkoxy carbamate synthesis and stimulus-responsive alcohol release

R. Adam Mosey, Paul E. Floreancig · Organic & Biomolecular Chemistry · 2012 · 38 citations · Full text

Structural Features, Engineering, Alcohol Release +6

Dihydroquinazolines enhance 20S proteasome activity and induce degradation of α-synuclein, an intrinsically disordered protein associated with neurodegeneration

Taylor J. Fiolek, Christina L. Magyar, Tyler J. Wall et al. · Bioorganic & Medicinal Chemistry Letters · 2021 · 32 citations · Full text

Proteasome, Molecular Biology, Synaptic Signaling +16

Synthesis of <i>tert</i>-Alkyl Amino Hydroxy Carboxylic Esters via an Intermolecular Ene-Type Reaction of Oxazolones and Enol Ethers

R. Adam Mosey, Jason S. Fisk, Timothy L. Friebe et al. · Organic Letters · 2008 · 28 citations

Active Natural Products, Bioorganic Chemistry, Engineering +15