MK-1775, a Potent Wee1 Inhibitor, Synergizes with Gemcitabine to Achieve Tumor Regressions, Selectively in p53-Deficient Pancreatic Cancer Xenografts

N.V. Rajeshkumar, Elizabeth De Oliveira, Niki A. Ottenhof, +8

Clinical Cancer Research

Systemic Administration of Polymeric Nanoparticle-Encapsulated Curcumin (NanoCurc) Blocks Tumor Growth and Metastases in Preclinical Models of Pancreatic Cancer

Savita Bisht, Masamichi Mizuma, Georg Feldmann, +11

Molecular Cancer Therapeutics

NanoparticlesEngineeringBiomedical EngineeringBlocks Tumor GrowthTumor Biology +17

Cyclin-dependent kinase inhibitor Dinaciclib (SCH727965) inhibits pancreatic cancer growth and progression in murine xenograft models

Georg Feldmann, Anjali Mishra, Savita Bisht, +14

Cancer Biology & Therapy

Very Long-term Survival Following Resection for Pancreatic Cancer Is Not Explained by Commonly Mutated Genes: Results of Whole-Exome Sequencing Analysis

Marco Dal Molin, Ming Zhang, Roeland F. de Wilde, +10

Clinical Cancer Research

Stromal galectin-1 expression is associated with long-term survival in resectable pancreatic ductal adenocarcinoma

Ru Chen, Sheng Pan, Niki A. Ottenhof, +8

Cancer Biology & Therapy

Surgical OncologyPrognosisPathologyLong-term SurvivalCancer Biology +17

Proteins associated with pancreatic cancer survival in patients with resectable pancreatic ductal adenocarcinoma

Ru Chen, David W. Dawson, Sheng Pan, +13

Laboratory Investigation

Tumor BiologyOncologyPancreatic CancerGastrointestinal OncologyMedicine +6

Molecular Characteristics of Pancreatic Ductal Adenocarcinoma

Niki A. Ottenhof, Roeland F. de Wilde, Anirban Maitra, +2

Pathology Research International

Tumor BiologyEngineeringTumor Guide TherapyPancreatic CancerPancreatic Fluid Collection +11

Pancreatic intraepithelial neoplasia and pancreatic tumorigenesis: of mice and men.

Niki A. Ottenhof, Anya N. Milne, Folkert H.M. Morsink, +4

PubMed

Analysis of LKB1 mutations and other molecular alterations in pancreatic acinar cell carcinoma

Roeland F. de Wilde, Niki A. Ottenhof, Marnix Jansen, +4

Modern Pathology

EngineeringPancreatic CancerOncogenic AgentMedicinePathology +9

Ectopic Overexpression of Sonic Hedgehog (Shh) Induces Stromal Expansion and Metaplasia in the Adult Murine Pancreas

Volker Fendrich, Edwin C. Oh, Seungmin Bang, +8

Neoplasia

Lineage PlasticityHuman PancreasSignal TransductionDevelopmental BiologyAdult Murine Pancreas +13