Kota Sudhakar Rao

Discovery of <i>N</i>-((4-([1,2,4]Triazolo[1,5-<i>a</i>]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1<i>H</i>-imidazol-2-yl)methyl)-2-fluoroaniline (EW-7197): A Highly Potent, Selective, and Orally Bioavailable Inhibitor of TGF-β Type I Receptor Kinase as Cancer Immunotherapeutic/Antifibrotic Agent

Cheng Hua Jin, Maddeboina Krishnaiah, D. Sreenu et al. · Journal of Medicinal Chemistry · 2014 · 160 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +10

Synthesis and biological evaluation of 1-substituted-3-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)pyrazoles as transforming growth factor-β type 1 receptor kinase inhibitors

Cheng Hua Jin, Maddeboina Krishnaiah, D. Sreenu et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 37 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Synthesis and biological evaluation of 1-substituted-3(5)-(6-methylpyridin-2-yl)-4-(quinoxalin-6-yl)pyrazoles as transforming growth factor-β type 1 receptor kinase inhibitors

Cheng Hua Jin, D. Sreenu, Maddeboina Krishnaiah et al. · European Journal of Medicinal Chemistry · 2011 · 35 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

Synthesis and biological evaluation of 1-substituted-3(5)-(6-methylpyridin-2-yl)-4-(quinolin-6-yl)pyrazoles as transforming growth factor-β type 1 receptor kinase inhibitors

Cheng Hua Jin, Maddeboina Krishnaiah, D. Sreenu et al. · Bioorganic & Medicinal Chemistry · 2011 · 32 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Synthesis and biological evaluation of 2-benzylamino-4(5)-(6-methylpyridin-2-yl)-5(4)-([1,2,4]triazolo[1,5-a]-pyridin-6-yl)thiazoles as transforming growth factor-β type 1 receptor kinase inhibitors

Maddeboina Krishnaiah, Cheng Hua Jin, D. Sreenu et al. · European Journal of Medicinal Chemistry · 2012 · 27 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15