In vivo supramolecular templating enhances the activity of multivalent ligands: A potential therapeutic against the <i>Escherichia coli</i> O157 AB ₅ toxins

Pavel I. Kitov, George L. Mulvey, Thomas P. Griener, +9

Proceedings of the National Academy of Sciences

Drug TargetPeptide EngineeringMolecular BiologyVivo Supramolecular TemplatingAnalytical Ultracentrifugation +18

Affinities of Shiga toxins 1 and 2 for univalent and oligovalent Pk-trisaccharide analogs measured by electrospray ionization mass spectrometry

Elena N. Kitova, Pavel I. Kitov, Eugenia Paszkiewicz, +5

Glycobiology

Multifunctional multivalency: a focused library of polymeric cholera toxin antagonists

Huu-Anh Tran, Pavel I. Kitov, Eugenia Paszkiewicz, +2

Organic & Biomolecular Chemistry

Bioorganic ChemistryPeptide EngineeringGlycobiologyGalactose ConjugatesAntimicrobial Chemotherapy +18

Synthesis and Immunochemical characterization of <i>S</i>‐linked Glycoconjugate Vaccines against <i>Candida albicans</i>

Xiangyang Wu, Tomasz Lipiński, Eugenia Paszkiewicz, +1

Chemistry - A European Journal

Ligand-assisted Aggregation of Proteins

Jason Ho, Pavel I. Kitov, Eugenia Paszkiewicz, +3

Journal of Biological Chemistry

Chemical BiologyProtein ChemistryCerebral Amyloid DepositsProtein AssemblyBiochemistry +11

Heterobifunctional Multivalent Inhibitor-Adaptor Mediates Specific Aggregation between Shiga Toxin and a Pentraxin

Dmitry Solomon, Pavel I. Kitov, Eugenia Paszkiewicz, +3

Organic Letters

Drug TargetToxinologyProtein AssemblyMultivalent Inhibitor-adaptorMolecular Biology +21

An Entropically Efficient Supramolecular Inhibition Strategy for Shiga Toxins

Pavel I. Kitov, Tomasz Lipiński, Eugenia Paszkiewicz, +8

Angewandte Chemie International Edition

Protein ChemistryMicrobial ToxinSupramolecular AssemblyProtein AssemblyBiochemistry +13

Design and Synthesis of a Universal Antigen to Detect Brucellosis

Julie Guiard, Eugenia Paszkiewicz, Joanna Sadowska, +1

Angewandte Chemie International Edition

Medical MicrobiologyBrucella SpeciesZoonotic DiseasePathogenesisImmunology +12

A Three Component Synthetic Vaccine Containing a β-Mannan T-Cell Peptide Epitope and a β-Glucan Dendritic Cell Ligand

David R. Bundle, Eugenia Paszkiewicz, Hassan R. H. Elsaidi, +2

Molecules

Synthesis of antifungal vaccines by conjugation of β-1,2 trimannosides with T-cell peptides and covalent anchoring of neoglycopeptide to tetanus toxoid

Jonathan Cartmell, Eugenia Paszkiewicz, Sebastian Dziadek, +5

Carbohydrate Research

AllergyT-cell PeptidesImmunologyTherapeutic VaccineCovalent Anchoring +7