James J. Lah

Variant of <i>TREM2</i> Associated with the Risk of Alzheimer's Disease

Thorlákur Jónsson, Hreinn Stefánsson, Stacy Steinberg et al. · New England Journal of Medicine · 2012 · 2.6K citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Early role of vascular dysregulation on late-onset Alzheimer’s disease based on multifactorial data-driven analysis

Yasser Iturria‐Medina, Roberto C. Sotero, P.-J. Toussaint et al. · Nature Communications · 2016 · 1.2K citations · Full text

Life Sciences, Neurology, Neuroscience +17

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

Rebecca Sims, Sven J. van der Lee, Adam C. Naj et al. · Nature Genetics · 2017 · 1.1K citations · Full text

Life Sciences, Neurobiology, Neuroscience +12

Large-scale proteomic analysis of Alzheimer’s disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation

Erik C. B. Johnson, Eric B. Dammer, Duc M. Duong et al. · Nature Medicine · 2020 · 1.1K citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Large-scale deep multi-layer analysis of Alzheimer’s disease brain reveals strong proteomic disease-related changes not observed at the RNA level

Erik C. B. Johnson, Kathleen Carter, Eric B. Dammer et al. · Nature Neuroscience · 2022 · 610 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +17