Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)¹

Daniel J. Klionsky, Amal Kamal Abdel‐Aziz, Sara Abdelfatah, +1267

Autophagy

Glucagon-Like Peptide 1 Protects Pancreatic β-Cells From Death by Increasing Autophagic Flux and Restoring Lysosomal Function

Francesco Paolo Zummo, Kirsty S. Cullen, Minna Honkanen‐Scott, +3

Diabetes

MitophagyAutophagic FluxImmunologyCell DeathCellular Physiology +17

Fructose 2,6-bisphosphate is essential for glucose-regulated gene transcription of glucose-6-phosphatase and other ChREBP target genes in hepatocytes

Catherine Arden, Susan J. Tudhope, John L. Petrie, +5

Biochemical Journal

Metabolic PathwaysSignal TransductionBiochemistryMedicineLiver Physiology +12

Elevated Glucose Represses Liver Glucokinase and Induces Its Regulatory Protein to Safeguard Hepatic Phosphate Homeostasis

Catherine Arden, John L. Petrie, Susan J. Tudhope, +5

Diabetes

Dual Role of Phosphofructokinase-2/Fructose Bisphosphatase-2 in Regulating the Compartmentation and Expression of Glucokinase in Hepatocytes

Victoria A. Payne, Catherine Arden, Chaodong Wu, +2

Diabetes

Glucokinase Is an Integral Component of the Insulin Granules in Glucose-Responsive Insulin Secretory Cells and Does Not Translocate During Glucose Stimulation

Catherine Arden, Andrew Harbottle, Simone Baltrusch, +2

Diabetes

Insulin GranulesCellular PhysiologyInsulin SignalingBioanalysisOrganelle Fractionation +20

A role for PFK-2/FBPase-2, as distinct from fructose 2,6-bisphosphate, in regulation of insulin secretion in pancreatic β-cells

Catherine Arden, Laura J. Hampson, Guo Huang, +7

Biochemical Journal

Insulin SignalingSignaling PathwayReceptor Tyrosine KinaseCell SignalingMolecular Physiology +16

Exendin-4 stimulates autophagy in pancreatic β-cells via the RAPGEF/EPAC-Ca²⁺-PPP3/calcineurin-TFEB axis

Francesco Paolo Zummo, Stanislaus Ivanovich Krishnanda, Merilin Georgiou, +7

Autophagy

Inhibition of glucokinase translocation by AMP-activated protein kinase is associated with phosphorylation of both GKRP and 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase

Mohammed Hasan Mukhtar, Victoria A. Payne, Catherine Arden, +4

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

Ampk ActivityInsulin SignalingProtein ExpressionSignaling PathwayAmp-activated Protein Kinase +21

A Novel Mechanism for Regulating Hepatic Glycogen Synthesis Involving Serotonin and Cyclin-Dependent Kinase-5

Susan J. Tudhope, Chung-Chi Wang, John L. Petrie, +7

Diabetes

Elevated Glycogen SynthesisInsulin SignalingGastrointestinal Peptide HormoneMetabolic SyndromeHepatotoxicity +19